Garth Nicolson’s Institute for Molecular Medicine


Garth Nicolson (, South Laguna Beach, CA) has been working for many years with leading rheumatology doctors, immune & biochemical scientists around the world and especially in the U.S. to diagnose persistent chronic infections related to arthritis, chronic fatigue, fibromyalgia, gulf war illness, Lyme disease, Mycoplasma, Chlamydia, Babesia, Ehrlichia,  multiple persistent viruses (especially HHVs), etc.  The persistent microbes that are involved are pleomorphic, with multiple stages/forms, multiple strains.  They invade multiple-tissue-types and cell-types. (blood, immune, epithelial, etc)


We last met Dr Nicolson at the Institute for Functional Medicine International Symposium in Seattle (April, 2011) where he was the Plenary Keynote Speaker.  The Challenge of Emerging Infections in the 21st Century: Terrain, Tolerance, and Susceptibility, The themes were explaining the biochemical mechanisms causing susceptibility to infections and systemic pathological dysfunctions.


Dr Nicolson has detailed practical treatments that are multi-antibiotic, multi factored, and multi-staged, with nutritional supplements, antimicrobial foods, and mitochondria-energy-enhancing supplements. See the references below. Included are papers by Dr. J.J. Burrascano on Lyme Disease “Advanced Diagnosis and Treatment Topics” and Dr Gabe Mirkin on why he uses antibiotics to treat rheumatic illnesses.


Dr Nicolson, Dr. Aristo Vojdani ( , Los Angeles) and Dr. A. Robert Franco (Arthritis Center of Riverside have together co-authored a significant number of important papers relating immune and antibody testing, nutritional assays, and chronic disease symptoms and treatment.


A list of Dr. Garth Nicolson’s and his collaborators’  most useful chronic-illness and treatment-related papers is found on his website, here : with the following disclaimer:

There are a number of considerations when undergoing therapy for chronic illnesses, including traditional medical approaches as well as integrative medicine approaches that utilize oxygen therapy, herbal therapy, and heat therapy, among others. The Institute for Molecular Medicine is a nonprofit institution and does not make specific recommendations for individual patients, nor does the Institute endorse commercial products. The types of products and procedures listed in this section are potentially useful; however, they are only examples of the types of approaches and substances that could be beneficial to patients with chronic illnesses. Consult your personal physician for advice on exact dosing and schedules, which can vary among individuals.


1.          Considerations when Undergoing Treatment for Chronic Illnesses and Autoimmune Diseases, by Prof. Garth L. Nicolson, Intern. J. Medicine 1998; 1:123-128. Plus Supplemental Suggestions: Prof. Nicolson 1/15/12. pdf_doc

2.          Lipid replacement and antioxidant nutritional therapy for restoring mitochondrial function and reducing fatigue in chronic fatigue syndrome and other fatiguing illnesses, by Prof. Nicolson, Journal of Chronic Fatigue Syndrome 2006; 13(1): 57-68. pdf doc

3.          Considerations When Undergoing Treatment For Gulf War Illness/Chronic Fatigue Syndrome, Fibromyalgia Syndrome, Rheumatoid Arthritis And Other Autoimmune Illnesses Reprinted from: The Intern. J. Medicine 1998;
1:123-128. Supplemental Suggestions: Prof. Nicolson 1/15/11

4.          Calcium Disodium EDTA Chelation Suppositories: a novel approach for removing heavy metal toxins in clinical practice, by R. Ellithorpe, T. Jimenez, B. Jacques, R. Settineri, L. Calpp and Garth L. Nicolson, In: Anti-Aging Therapeutics, R. Klatz and R. Goldman, eds., vol. 11, American Academy of Anti-Aging Medicine, 2009: 107-118. pdf doc

5.          Lipid replacement therapy: a nutraceutical approach for reducing cancer-associated fatigue and the adverse effects of cancer therapy while restoring mitochondrial function, by Prof. Garth Nicolson. Cancer &
Metastasis Reviews
2010; 29(3): 543-552. pdf doc

6.          Lipid replacement as an adjunct therapy in chronic fatigue, anti-aging and restoration of mitochondrial function, by G. L. Nicolson, JANA 2003; 6(3): 22-28. pdf doc

7.          Nutritional Supplement (NT Factor) Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects, by M. Agadjanyan, et al. J. Chronic Fatigue Syndrome. 2003; 11(3): 23-36. rtf doc

8.          Pilot Study: Reduction of fatigue by use of a dietary supplement containing glycophospholipids, by Ellithorpe et al., JANA 2003; 6: 23-28. pdf doc

9.          Diagnosis and Integrative Treatment of Intracellular Bacterial Infections in Chronic Fatigue and Fibromyalgia Syndromes, Gulf War Illness, Rheumatoid Arthritis and other Chronic Illnesses. Clinical Practice of Alternative Medicine 2000; 1(2): 42 - 102 rtf doc

10.     Identification and Treatment of Chronic Infections in CFIDS, Fibromyalgia Syndrome and Rheumatoid Arthritis. CFIDS Chronicle 1999; 12(3): 19-21  rtf doc


1.          Notes On Morgellons Syndrome (Disease), Contributors to this information: Cheryl Nichols, Prof. Garth Nicolson, The Institute for Molecular Medicine and The Morgellons Research Foundation, Revised Patient Information (Updated 2/2/09) rtf doc

2.          Advanced Topics in Lyme Disease: Diagnostic hints and treatment guidelines for Lyme and other tick borne illnesses by J.J. Burrascano, Jr., Managing Lyme Disease, 16th Edition, 2008. pdf doc

3.          Diagnosis and therapy of chronic systemic co-infections in Lyme Disease and other tick-borne infectious diseases, by Prof. Garth Nicolson, Townsend Letter for Doctors& Patients,  2007; 285: 93-98  pdf doc

4.          Treatment Considerations for Autistic Spectrum Disorder Patients at the Institute for Molecular Medicine, by Prof. G. Nicolson, 2006  rtf doc

5.          Suggested therapy of chronic systemic Chlamydial and Chlamydial/Mycoplamal co-infections, by Prof. Garth Nicolson, 2005 rtf doc

6.          Diagnosis and Therapy of Chronic Systemic Co-Infections in Lyme Disease and Other Tick-Borne Infectious Diseases, American College for Advancement in Medicine, by Prof. Garth Nicolson, 2006  rtf doc

7.          Chronic Fatigue, Aging, Mitochondrial Function and Nutritiional Supplements, by Prof. Garth Nicolson, Townsend Letter for Doctors & Patients 2003; 240(7): 72-76. -  pdf_doc

8.          Fighting Those Persistent INFECTIONS In CFIDS By Jacob Teitelbaum, From Fatigued to Fantastic Newsletter 2000; 3 and 2001; 4 newsletters rtf doc

9.          Research Overview: Professor Garth Nicolson's Studies and Treatments Explained By Deborah Cooper, Treatment & Research Library, 2006  rtf  doc

10.      Why I Prescribe Antibiotics. By Gabe Mirkin, M.D., 2000 rtf doc

11.      Dietary Considerations for Patients with Chronic Illnesses and Multiple Chronic Infections: A Brief Outline of Eighteen Dietary Steps to Better Health by Garth Nicolson and Richard Ngwenya, Townsend Letter for Doctors& Patients 2001; 219:62-65. rtf doc