Chapter
3 Endnotes for Arthritis and Autoimmune Disease: The Infection Connection
How
Infection Works
1) Rose NR, Bona C.
"Defining criteria for autoimmune diseases (Witebsky's postulates
revisited)". Immunol. Today 14 (9): 426–30. (September 1993).
2) The autoimmune
theory is underscored repeatedly in immunology textbooks such as Bittar, EE and
Bittar, N. Immunobiology, Elsevier (1996) pg 240, and also in various
articles in Arthritis Today, the
publication of the Arthritis Foundation. The original autoimmune theory appears
in Rose and MacKay (3rd edition, 1986) but updated in their 4th
edition (2006). An example of a more realistic view is “Interview with
evolutionary biologist Paul Ewald” by Amy Proal at http://bacteriality.com/2008/02/11/ewald/.
Also see http://bacteriality.com/2008/05/26/biofilm/ Also on this website are lots of useful data
on Chronic Disease and the Marshall Protocol. Another good reference is http://www.immed.org/illness/autoimmune_illness_research.html
3) Brown and
Scammell (1988) pp. 78-79. Assorted childhood rheumatic infections are part of
Katherine Poehlmann’s medical history (bronchitis, strep throat, pneumonia).
4) See www.rheumatic.org
for paper citations, case studies, laboratory results, abstracts, and so forth.
An impressive paper by Dr. Joseph M. Mercola, D.O., “Protocol for Using
Antibiotics in the Treatment of Rheumatic Diseases,” can be found at www.mercola.com.
The paper was presented at the 31st Annual Meeting of the American Academy of Environmental
Medicine in Boston, MA in October 1996. Dr. Mercola lauds Dr. Brown’s
pioneering work in mycoplasma research and tetracycline treatment. His paper
essentially expands on Dr. Brown’s and Henry Scammell’s fundamental work, The Road Back. Dr. Mercola offers a
description of the original protocol using minocycline in Appendix II of this
book. This text is written by a physician for physicians and may be difficult
for the layperson to understand. Dr. Mercola has improved upon the protocol by
introducing a nutritional regimen to strengthen the immune system. See details
at www.mercola.com.
5) Blumberg, Dr.
Darren R. and Sloan, Dr. Victor S. of the Robert Wood Johnson Medical School,
New Brunswick, New Jersey in a letter “Classification of Reactive Arthritides.”
6) Also see Veys
E.M. and Mielants, H. “Enteropathic Arthropathies.” In: Klippel and Dieppe
(1994).
7) Sieper, J,
Braun, J, “Editorial: Treatment of Reactive Arthritis with Antibiotics.” British
Journal of Rheumatology, 1998, 37(7), 717-720
8) Newkirk MM, et
al. “Elevated levels of IgM and IgA antibodies to Proteus mirabilis and
IgM antibodies to Escherichia coli are associated with early rheumatoid
factor (RF)-positive rheumatoid arthritis.” Rheumatology (Oxford) 2005;44:1433-41.Also
Ebringer A, Rashid T. “Rheumatoid arthritis is an autoimmune disease triggered
by Proteus urinary tract infection.” Clin Dev Immunol. 2006
Mar;13(1):41-8. An impressive body of
research on P. mirabilis and its role in RA has been done by Alan
Ebringer. E.g., http://www.ncbi.nlm.nih.gov/pubmed/16603443 and
other articles on PubMed.
9) Wilson R.
“Treatment of COPD exacerbations: antibiotics.” Eur Respir Rev 2005 Sept vol. 14 no. 94 32-38. http://err.ersjournals.com/content/14/94/32.full. Also Hunter
MH, M.D. and King DK, M.D. “COPD: Management of Acute Exacerbations and Chronic
Stable Disease.” Am Fam Physician. 2001 Aug 15;64(4):603-613. Online at www.aafp.org/afp/2001/0815/p603.html.
Also www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/
10) NIH
Backgrounder. (Unattributed article). “Stress System Malfunction Could Lead to
Serious, Life Threatening Disease” (2002) www.nichd.nih.gov/news/releases/stress.cfm
11) Fogoros RN, M.D.
“Metabolic Syndrome.” Online at http://heartdisease.about.com/cs/cholesterol/a/metsynx.htm
(2008)
12) http://www.mayoclinic.com/health/metabolic%20syndrome/DS00522
13) www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004546/ (2011)
14) www.potbellysyndrome.com/attach/PBS_Summary.pdf
15) Nabipour I,
Vahdat K, et al. “The association of metabolic syndrome and Chlamydia
pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus type
1: the Persian Gulf Healthy Heart Study.” Cardiovasc Diabetol. 2006 Dec
1;5:25. Online at www.ncbi.nlm.nih.gov/pubmed/17140429
16) Goldstone, T, et
al. “Stomach hormone ghrelin increases desire for high-calorie
foods.”Presentation at The Endocrine Society’s 92nd Annual Meeting in San
Diego, CA, June 2010.
17) Mårin and Farris
(2005)
18) Henley DE, et
al. “Hypothalamic-pituitary-adrenal axis activation in obstructive sleep apnea:
the effect of continuous positive airway pressure therapy.” J Clin
Endocrinol Metab. 2009 Nov;94(11):4234-42. Online at www.ncbi.nlm.nih.gov/pubmed/19820009
19) www.drmercola.com/sleep/how-lack-of-sleep-can-damage-your-health/
20) Find a wealth of
dental infection information at http://www.biofilmcommunity.org/f11/. Also see
George E. Meinig, DDS Root Canal Cover-Up (1994) See biofilms at http://bacteriality.com/2008/05/26/biofilm/
21) Baumgartner S,
Imfeld T, et al. “The impact of the stone age diet on gingival conditions in
the absence of oral hygiene.” J Periodontol. 2009 May;80(5):759-68.
22) http://rheumatic.org/teeth.htm
23) Touyz LZ. “Oral
scurvy and periodontal disease.” J Can Dent Assoc. 1997
Dec;63(11):837-45. Online at www.ncbi.nlm.nih.gov/pubmed/9433025
24) Sparks SP,
Desrosiers M, Donegan SJ, et al. “Tooth loss, dementia and neuropathology in
the Nun Study.” J Am Dent Assoc 2007;138:1314–1322
25) Elizabeth Kaye,
MPH, PhD. “Periodontal Disease and impaired cognition.” June, 2010. Online at www.aragonadentistry.com
26) Liao F, Li Z, et
al. “Porphyromonas gingivalis may play an important role in the pathogenesis of
periodontitis-associated rheumatoid arthritis.” Med Hypotheses. 2009
Jun;72(6):732-5.
27) http://www.nih.gov/news/health/nov2011/nidcr-29.htm
28) Conversation
with Dr. Jack Davis, a dentist practicing in Greer, SC.
29) Dr. Aristo
Vojdani’s intense interest in the study of infectious diseases began when his
mother was diagnosed with RA after her dental surgery led to a bacterial
infection. His California lab does comprehensive testing for autoimmunity, Lyme
Disease, bacterial and viral diseases. See www.immunoscienceslab.com
30) http://dent.umich.edu/media/research/loeschelabs/abs7.45.html
31) http://rheumatic.org/teeth.htm
32) McCabe (1988 and
2004)
33) Sadly, their
findings and subsequent research were deliberately ignored. http://www.arthritistrust.org/Articles/Root%20Canal%20Coverup%20Conceals%20Numerous%20Side%20Effects/index.htm
35) http://www.k-state.edu/parasitology/625tutorials/Egingivalis.html
36) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669679/
(2008)
37) Also see Garten
(1978) for excellent information on dental infections and metal amalgams.
38) This section
includes insights from a presentation by Dr. Charles W. Stratton at the 2011
IFM international conference on infectious diseases in Bellevue, WA. Also see a
comprehensive reference,“The Chlamydia Pneumoniae Handbook” at http://www.cpnhelp.org/book/export/html/408
39) Until 2009, this
organism was known as Chlamydia pneumoniae, but both names are now used
interchangeably. See www.ncbi.nlm.nih.gov and use the search window
with either term to find publications.
40) Find an
excellent overview of all the Chlamydiaceae family at http://pathmicro.med.sc.edu/mayer/chlamyd.htm.
41) www.cpnhelp.org/chlamydia_pneumoniae_anti
42) See more about
this test at www.chronicneurotoxins.com/
43) Johanning
(2005).
44) www.ncbi.nlm.nih.gov/pmc/articles/PMC163910/ (1997)
45) This section
includes insights from a presentation by Dr. David Perlmutter at the 2011 IFM
international conference on infectious diseases in Bellevue, WA.
46) Letenneur L, et
al. “Seropositivity to herpes simplex virus antibodies and risk of Alzheimer's
disease: a population-based cohort study.” PLoS One.
2008;3(11):e3637. Online at www.ncbi.nlm.nih.gov/pubmed/18982063
47) Itzhaki RF,
Wozniak MA. “Herpes simplex virus type 1 in Alzheimer's disease: the enemy
within.” J Alzheimers Dis. 2008 May;13(4):393-405. Also Wozniak MA, Mee
AP, Itzhaki RF. “Herpes simplex virus type 1 DNA is located within Alzheimer's
disease amyloid plaques.” J Pathol. 2009 Jan; 217(1):131-8. Statistics
at www.alz.org/national/documents/report_alzfactsfigures2009.pdf
48) Porcellini E, et
al. “Alzheimer’s disease gene signature says: beware of brain viral
infections.” Immunity & Ageing 2010, 7:16 . Online at http://www.immunityageing.com/content/7/1/16
49) Soscia SJ, Kirby
JE, et al. “The Alzheimer's disease-associated amyloid beta-protein is an
antimicrobial peptide.” PLoS One. 2010 Mar 3;5(3):e9505.
50) Rubey RN. “Could
lysine supplementation prevent Alzheimer's dementia? A novel hypothesis.” Neuropsychiatr
Dis Treat. 2010 Oct 27;6:707-10.
51) http://www.vitamincfoundation.org/collagen.html
52) http://internetwks.com/owen/gorilla3.htm
discusses how chronically low levels of vitamin C contribute to heart disease.
Tests on zoo gorillas using vitamin C supplements achieved dramatic results.
53) www.ourhealthcoop.com/newsletter/news_unified_theory.htm
(2004) and www.paulingtherapy.com/
54) Personal
communication with Dr. Garth Nicolson, January 2002.
55) http://emedicine.medscape.com/article/966785-overview#a0104 (2010)
56) “Mycoplasmal
Infections,” a well-documented, detailed overview, is provided without charge
to Institute for Molecular Medicine visitors to www.immed.org.
57) http://www.rain-tree.com/mycoresearch.htm
and http://emedicine.medscape.com/article/223609-overview -
a0199
58) About 3 Tbs per
day of coconut oil (lauric acid) would suffice to dissolve microbes’ lipid
envelopes in the gut, lymph system, and blood.
59) www.naturalnews.com/026819_lauric_acid_coconut_oil.html
(2009)
60) Simmons WL and
Dybvig K. “Mycoplasma Biofilms Ex Vivo and In Vivo.” FEMS Microbiol Lett.
2009 June; 295(1): 77–81. Online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703428/
61) Research
conducted primarily by Dr. Albert Sabin, who worked with Dr. Brown at the
Rockefeller Institute during the 1930s. Also see Simecka, J. W., et al.
“Mycoplasma Diseases of Animals.” in Maniloff (1992) section V, chapter 24.
62) All quotes
attributed to Drs Baseman and Tully in this chapter may be found at www.cdc.gov/ncidod/EID/vol3no1/baseman.htm.
63) Toppo (1986), p.
52. Also Pelton, R. et al., Drug-Induced Nutrient Depletion Handbook. Lexi
Comp, Inc. 2001.
64) Murray, et al.
(2009) Chapter 6 (Bacteriology by Dr. Gene Mayer. Online at http://pathmicro.med.sc.edu/mayer/antibiot.htm
65) Cassel, G.H and
Mekalanos J. “Development of Antimicrobial Agents in the Era of New and
Reemerging Infectious Diseases and Increasing Antibiotic Resistance.” JAMA Feb 7 2001; 285(5), 601-5.
66) Scammell (1998)
p. 132.
67) Hunter MH, M.D.
and King DK, M.D. “COPD: Management of Acute Exacerbations and Chronic Stable
Disease.” Am Fam Physician. 2001 Aug 15;64(4):603-613. Online at www.aafp.org/afp/2001/0815/p603.html.
Also www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/
68) Wilson R.
“Treatment of COPD exacerbations: antibiotics.” Eur Respir Rev 2005 Sept vol. 14 no. 94 32-38. http://err.ersjournals.com/content/14/94/32.full.
69) McManus TE, et
al. “High levels of Epstein–Barr virus in COPD.” Eur Respir J
2008; 31: 1221–1226
70) Drs Baseman and
Tully (1997): .”..pathogenic mycoplasmas are among the most difficult
microorganisms to grow from clinical specimens and remain frequent contaminants
of primary and continuous eucaryotic cell lines and tissue cultures. In some
instances, mycoplasma contamination is obvious since infected eucaryotic cells
exhibit aberrant growth, metabolism, and morphology. However, mycoplasmas often
establish covert and chronic infections of target cells that lead to either
invalid and misleading data or introduction of mycoplasmas or their products
into reagents dedicated to therapeutic or research purposes.”
71) Engelhard,
Victor H. “How Cells Process Antigens.” Scientific
American, August 1994. Also “The
Immune System–Overview”(2011) at http://NobelPrize.org/educational/medicine/
immunity/immune-overview.html.
72) Personal
communication with Dr. Garth Nicolson, January 2002.
73) Garrett (1995)
pp. 572-5.
74) Ataoglu, H.;
Goksu, N.; Kemaloglu, Y.K.; Bengisun, S.; and Ozbilen, S. “Preliminary Report
on L-forms: Possible Role in the Infectious Origin of Secretory Otitis Media.” Annals of Otology, Rhinology and
Laryngology. June 1994; 103:6, 434-8.
75) Watson, P.,
Voss, L., et al. “The Microbiology of Chronic Otitis media with Effusion in a Group of Auckland Children.” New Zealand Medical Journal. May
1996;109:1022, 182-4.
76) Mel'nikoava NN,
Mokrousova IV. “Study of rifampicin resistance in L-forms of Mycobacterium
tuberculosis, by analyzing rpoB gene mutations.” Probl Tuberk Bolezn
Legk. 2006;(11):22-4. [in Russian]
77) Nicolson, Garth
L.; Nasralla, Marwan Y.; and Nicolson, Nancy L. “The Pathogenesis and Treatment
of Mycoplasmal Infections.” Antimicrobics
and Infectious Disease Newsletter. 1999;17(11): 81-8.
78) See www.psa-rising.com/medsci/p53.htm
(2000). Also Carvalho JR, Filipe L, et al. “Detailed analysis of expression and
promoter methylation status of apoptosis-related genes in prostate cancer.” Apoptosis.
2010 Aug;15(8):956-65. www.ncbi.nlm.nih.gov/pubmed/20464497
79) Gdoura R, et al.
“Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma
parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void
urine specimens of asymptomatic male partners of infertile couples.” J Androl.
2008 Mar-Apr;29(2):198-206. Online at www.ncbi.nlm.nih.gov/pubmed/18077823.
80) http://mpkb.org/home/arf/timeline
shows a detailed history of the development of the Marshall Protocol, with hot
links to many informative publications and research findings.
81) www.riordanclinic.org/research/articles/89022715.pdf (2003)
82) Park, H. J.,
Lee, S.H., et al. "Antiarthritic Effect of Bee Venom: Inhibition of
Inflammation Mediator Generation by Suppression of NF-êB Through Interaction
With the p50 Subunit." Arthritis & Rheumatism, November 2004;
50:11; pp. 3504-3515.
83) Rothfeld, Glenn,
M.D. “About Bee Venom Therapy.” Online, with many references to scientific
literature on bee products, bee venom, and other types of venom, at http://www.naturodoc.com/library/bee_venom/bvt_spectrum.htm
84) Roberts, MC.
“Antibiotic Resistance.” in Maniloff (1992), section V, chapter 31.
85) Brandt DB, et
al. “The Promise of a Tetracycline Antibiotic for Treating Osteoarthritis.” Arthritis
& Rheumatism. 2005;52(7):2015-2025. Online at www.medscape.com/viewarticle/509929
86) Hunter MH, M.D.
and King DK, M.D. “COPD: Management of Acute Exacerbations and Chronic Stable
Disease.” Am Fam Physician. 2001 Aug 15;64(4):603-613. Online at www.aafp.org/afp/2001/0815/p603.html.
87) Wilson R.
“Treatment of COPD exacerbations: antibiotics.” Eur Respir Rev 2005 Sept vol. 14 no. 94 32-38. http://err.ersjournals.com/content/14/94/32.full.
88) www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/
89) Appendix:
“Antibiotics: Efficacy Against Susceptible Pathogens.” Physician’s Drug Handbook (2007).
90) www.nlm.nih.gov/medlineplus/druginfo/meds/a682098.html
(2008)
91) www.peacehealth.org/xhtml/content/cam/hn-1514007.html
lists herb and vitamin interactions with tetracycline.
92) See www.drugs.com/drug-interactions/tetracycline.html
93) Malley, Beth A.
“The Use of Minocycline in the Treatment of Rheumatoid Arthritis.” For a PDF of
this article, click here or Google “encognitive townsend
letter minocycline”
94) BC Tilley, GS
Alarcon, et al, “Minocycline in Rheumatoid Arthritis: a 48 Week, Double-Blind,
Placebo-Controlled Trial,” Ann Int Med, 1995; 122:2, pg 81 -89.
95) O’Dell, J.R.; Paulsen, G.; Haire, C.E.; et al. “Treatment of
Early Seropositive Rheumatoid Arthritis with Minocycline: Four-year Followup of
a Double-blind, Placebo-controlled Trial.” Arthritis
and Rheumatology 1999;42:1691-1695.
96) See www.drmirkin.com/joints/J106.htm.
“Arthritis Treatments.”
97) www.drmirkin.com/joints/3013.html
98) Haier J,
Nasralla M, Franco AR, and Nicolson GL.“Detection of mycoplasmal infections in
blood of patients with rheumatoid arthritis.” Rheumatology 1999;38(6):
504-509.
99) http://www.drmirkin.com/joints/J159.htm
(2010)
100) http://www.drmirkin.com/morehealth/g221.html (2005)
101) http://www.drmirkin.com/joints/J106.htm
(2011)
102) See www.thearthritiscenter.com.
This is an excellent and comprehensive website with many informative articles
on chronic illnesses.
103) Scammell (1998)
p. 212.
104) Mandell (1983) chapter 5.
105) Brown and
Scammell (1988) chapter 15.
106) www.inchem.org/documents/jecfa/jecmono/v041je07.htm
107) Ongoing
microbiology research by Dr. Stuart Levy, Tufts University. www.tufts.edu/med/microbiology/lab/levy/projects/tet.html.
108) “Functional
Anatomy of Prokaryotic and Eukaryotic Cells.” Chapter 4 of textbook by Tortora,
et al (2006). Online at
www.pearsonhighered.com/tortora10einfo/assets/pdf/TortoraFunkeCase_10e_CH04.pdf
109) Sánchez-Vargas
FM, Gómez-Duarte OG, “Mycoplasma pneumoniae—an emerging extra-pulmonary
pathogen.” Clinical Microbiology and Infection. Volume 14, Issue 2,
pages 105–115, Feb 2008. Online at http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2007.01834.x/full
110) Baum (2005)
111) Brown and
Scammell (1988) chapter 23.
112) See www.mercola.com/nutritionplan/index2.htm
for Dr. Mercola’s comprehensive three-part program. He has helped thousands of
his patients who make a commitment to this admittedly difficult but ultimately
rewarding dietary plan.
113) http://rheumatic.org/malis.htm.
This site lists several doctors who will administer the antibiotic protocol: http://rheumatic.org/docs.htm
114) This section
represents insights obtained at the Institute for Functional Medicine’s 2011
international symposium “The Challenge of Emerging Infections in the 21st
Century.” Notably, Dr. Michael Ash’s presentation “Living with the Host: Immune Programming and Clinical
Implications.”
115) Dubois, B, et
al. “Sequential role of plasmacytoid dendritic cells and regulatory T cells in
oral tolerance.” Gastroenterology. 2009 Sep. 137(3): 1019-28.
116) Maynard, CL,
Weaver, CT. “Intestinal T cells in health and disease.” Immunity 2009
Sep 16:31(3);388-400. Review.
117) The chemicals in
Lavoris® mouthwash have been known to kill the bacteria that cause GERD. These
are zinc oxide, sodium hydroxide, and citric acid..
118) A procedure
called Transnasal Esophagoscopy (TNE) gives physicians a new and more effective
way to detect esophageal tumors. http://news.healingwell.com/index.php?p=news1&id=653947 (2011) Dr. Jonathan Aviv has demonstrated
the technique on the Dr. Oz Show.
119) Presentation by
Dr. Sandra Macfarlane at the 2011 International IFM conference in Bellevue, WA
120) One example is
Macfarlane S, Dillon JF. “Microbial biofilms in the human gastrointestinal
tract.” J Appl Microbiol. 2007 May;102(5):1187-96. Online at www.ncbi.nlm.nih.gov/pubmed/17448154
121) See “Gut
Bacteria and Health Countermeasures” at www.ra-infection-connection.com/gut health.htm
(2011)
122) Protocol
for Antibiotic Therapy, from The Road Back Foundation at www.roadback.com.
123) Murray, et al. Medical
Microbiology, 2005, chapter 40.
124) www.livescience.com/3092-human-gut-loaded-bacteria-thought.html
(2008)
125) http://cardiovascres.oxfordjournals.org/content/73/2/341.full
(2006) Also search on keywords “disbacteriosis” and “dysbiosis” at
www.gastro.org
126)
See details at www.bacteriamuseum.org/cms/Food-And-Water-Safety/good-bacteria-in-food.html (2009)
127) See “A
Revolution in Our Understanding of Oils and Nutrition” at www.ra-infection-connection.com/OilNutrnRevln.htm
128)
This short subsection is not intended to be prescriptive.
There are a great many health texts which give detailed information on a
balanced diet specifically for countering yeast infections. See, for example, Crook (1986, 1995) and
also www.naturalhealthmag.com/healthy-eating/anti-inflammatory-diet
(2011) and www.mercola.com
(use the search window on this website).
129) Communication
with nutritionist Dr. Victoria Arcadi, who states that 60-80% of her patients
have systemic yeast overgrowth.
130) www.betterhealthusa.com/public/159.cfm
131) www.nationalcandidacenter.com/leaky-gut/
(2007)
132) There are many
books and informative websites on this topic, e.g., www.safecoloncleanse.com
and www.mysticmedicine.com.
Harsh laxatives are not recommended.
133) Waling, E.
“Apple Cider Vinegar is Effective Treatment for Candida.” (2009). Online at www.naturalnews.com/025452_vinegar_apple_cider.html.
134) Lawson, C. “Cure
Yeast Infection Naturally With Garlic.” The American Chronicle. (2009).
135) Crook ( 1986)
and Crook (1995)
136) www.yeastinfectioncure101.com/
137) Cho SS and
Finocchiaro T. (2010)
138) Find a complete
list at www.prebsuperfood.com/articles5d6c.html?ID=163
139) Find details at www.ra-infection-connection.com/Kefirprobiotics.htm
140) See www.mercola.com/2001/jul/11/probiotics.htm.
141) www.whitakerwellness.com/
142) Overview with
many references: www.energeticnutrition.com/vitalzym/serrapeptase.html#carpal
143) http://articles.mercola.com/sites/articles/archive/2011/08/21/enzymes-special-report.aspx
144) Find details at http://www.bromelain.net/
145) Painter, FM.
“Bromelain Monograph.” Altern Med Rev Aug 1998:3(4)302-30. Online at http://www.thorne.com/altmedrev/.fulltext/3/4/302.pdf
Overview with many scientific references.
146) Cichoke and
Hoffer (2000)
147) Fraser R, Ingram
MC, et al. “Cortisol Effects on Body Mass, Blood Pressure, and Cholesterol in
the General Population.” Hypertension. 1999;33:1364-1368. Online at http://hyper.ahajournals.org/content/33/6/1364.full
148) Diagram online
at www.humpath.com/IMG/jpg_global_metabolism_0807_hij.jpg
149) http://en.wikipedia.org/wiki/File:Citric_acid_cycle_with_aconitate_2.svg
150) Bergman, J. “ATP
The Perfect Energy Currency for the Cell.” Creation Research Society
Quarterly, Vol 36, No.1. 1999. Online at http://www.trueorigin.org/atp.asp
Excellent overview with diagrams.
151) http://kentsimmons.uwinnipeg.ca/cm1504/krebscycle.htm.
Textbook overview with diagrams.
152) Mevalonate
pathway mechanism at http://flipper.diff.org/app/pathways/14
153) Unattributed
article. “Cholesterol-Reducing Drugs May Lessen Brain Function, Says
Researcher.” ScienceDaily (Feb. 23, 2009) Online at http://www.sciencedaily.com/releases/2009/02/090223221430.htm
154) www.joimr.org/JOIMR_Vol7_No1_Dec2009.pdf
155) O’Riordan, M.
“Statin-induced myopathy reflects structural muscle damage, new study shows.”
7/6/2009. Online at http://www.theheart.org/article/984185.do
156) Details at www.ra-infection-connection.com/coq10andstatins.htm
157) Article by the
late Dr. H.A. Nieper on serrapeptase and carotid artery blockage: http://serrapeptase.info/category/articles/.
Also see the forum on serrapeptase at www.themiracleenzyme.info/
158) Sharma AK. “A
Preliminary trial of Serratiopeptidase in patients with Carpal Tunnel
Syndrome.” J Assoc Phy India. 2000;48:1130.
159) Unattributed
article. “Serrapeptase Insect-Derived Enzyme Fights Inflammation.” Online at http://intelegen.com/nutrients/serrapeptase.htm
(2001)
160) Selan L,
Berlutti F, et al. “Proteolytic enzymes: a new treatment strategy for
prosthetic infections?” Antimicrob Agents Chemother. 1993;
37(12):2618-21.
161) See www.ra-infection-connection.com/countermeasures.htm
162) Ma G and Allen
HC. “New Insights into Lung Surfactant Monolayers Using Vibrational Sum
Frequency Generation Spectroscopy.” Photochemistry and Photobiology,
2006, 82: 1517–1529. Online at http://research.chemistry.ohio-state.edu/allen/files/2011/09/34.pdf
163) Howell (1995)
164) http://www.drmirkin.com/nutrition/1451.html (2005)
166) Howell (1995)
167) www.aomega.com/minerals/minerals.htm.
This reference and information guide is comprehensive and useful. Although it
appears on a commercial vitamin/supplement site, citing the guide does not mean
that Dr. Poehlmann receives any compensation or endorses any products sold on
the website.
169) More detail at www.ra-infection-connection.com/naturalantivirals.htm
and www.ra-infection-connection.com/OilNutrnRevln.htm
170) www.aromabar.com/articles/baud55.htm
171) Brown and
Scammell (1988) chapter 7.
172) A good rule of
thumb: every pound of excess weight exerts 4 pounds of pressure on knee and
ankle joints.
173) Maksymowych,
W.P.; Ikawa, T.; Yamaguchi, A.; Ikeda, M., et al. “Invasion by Salmonella
typhimurium Induces Increased Expression of the LMP, MECL, and PA28
Proteasome Genes and Changes in the Peptide Repertoire of HLA-B27.” Infection
& Immunity. 66: 4624-32, 1998.
174) Ikawa, T.;
Ikeda, M.; Yamaguchi, A.; Tsai, W.C., et al. “Expression of Arthritis-causing HLA-B27 on Hela Cells
Promotes Induction of C-Fos in Response to in vitro Invasion by Salmonella
typhimurium.” Journal of Clinical Investigation. 101: 263-72,
1998.
175) Adams JS, Lee G.
“Gains in bone mineral density with resolution of vitamin D intoxication. Ann
Intern Med 1997;127:203–6. Online at http://www.annals.org/content/127/3/203.full
176) http://mpkb.org/home/arf/timeline
shows a detailed history of the development of the Marshall Protocol, with hot
links to many informative publications and research findings.
177) Olszewski (1987)
pp. 123-127. See also Vinh, DC, Embil, JM "Severe skin and soft tissue
infections and associated critical illness". Curr Infect Dis Rep 9
(5): 415–21, September 2007.
178) www.ra-infection-connection.com/OilNutrnRevln.htm
179) www.apccsec.org/document/ENIG.pdf
and http://coconut-info.com/mary_enig_cholesterol.htm.
The last is a commercial site but the article presented is useful and
informative. Dr. Poehlmann does not support or endorse any commercial products.
Her efforts are completely nonprofit. Google “Enig fats oils” to find many of
her papers and online references.
180) www.coconutoil.com
181) www.alternative-healthzine.com/html/0108_2.html
182) Kandasamy P,
Zarini S, Chan ED, et al. “Pulmonary surfactant phosphatidylglycerol inhibits
Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse
macrophages.” J Biol Chem. 2011 Mar 11;286(10):7841-53
183) See www.arthritistrust.org/Articles/Mycoplasmas
Properties & Their Role in Autoimmune Diseases/index.htm (August 1999 presentation by Dr. Harold
Clark as a lecture series)
184) Connor, J.F.,
DVM. “Early Pig Vaccination Disease Breakthrough Mycoplasmal Pneumonia Vaccine
for Young Pigs Shows Promise.” (2009). Online at http://nationalhogfarmer.com/health-diseases/115-early-mycoplasmal-vaccine-promise
185) www.pfizer.com/files/news/press_releases/2010/amc_032310.pdf
186) See www.mckinley.illinois.edu/handouts/immunoglobulin.html
187) Michaud (1989) chapter
9. Also “The Immune System–Overview”(2011) at http://NobelPrize.org/educational/medicine/immunity/immune-overview.html
188) Culhane, Kari W.
“Allergy Antidotes for Kids.” Natural
Health, March/April 2000.
189) Michaud (1989)
pp. 64-5.
190) Mandell, Dr.
Marshall (1988) Megadoses of any vitamin are not recommended over time. The
large amounts he suggests are for a specific and intense allergic reaction, not
for daily intake, even as a preventive measure.
191) Personal
communication with Dr. Garth Nicolson, January 2002.
192) www.earthclinic.com/CURES/sinus_polyps.html
193) Ullman D and Frass
M. “A Review of Homeopathic Research in the Treatment of Respiratory
Allergies.” Alternative Medicine Review, Vol 15, Number 1. (2010).
Online at www.thorne.com/altmedrev/.fulltext/15/1/48.pdf
Also see www.healthy.net/Health/Article/Homeopathy_and_Sinusitis_Safer_Remedies/946
.
194) Visit www.herbs2000.com/homeopathy/1_homeopathy.htm, enter the homeopathic remedy in the search window to find details of conditions to which it applies. The site contains many informative articles and references. Also search by condition to find applicable natural remedies.
