Dangers of Statin Drugs Blocking CoQ10 Synthesis

Side effects of Lipitor, Zocor, Pravachol, Mevacor, and other cholesterol-lowering statin drugs.

Generic Names: lovastatin,, atorfastatin, rosuvastatin, fluvastatin, pravastatin, imvastatin, ezetimbe/simvastatin. (Sometimes with niacin)

HMG-CoA reductase inhibitors (statins) block CoQ-10 synthesis. [Google: mevalonate pathway]

· CoQ10 is essential to life, cellular energy release, mitochondrial health.

· CoQ10 deficiencies increase the rates of aging.

· CoQ10 need is ~ 500 mg/day; amount made in liver is decreased by >50% or more depending on dosage of statins.

· CoQ10 in food is 5-10 mg per day; supplements are needed after age 40.

· CoQ10 supplementation will reverse only some of the statins’ side effects.

· Too low cholesterol causes neuropathy and degenerative changes in muscles and nerves.

Questioning the premise lowering the cholesterol level is beneficial: False

• The premise statins are safe is falsified by the following paper: Adverse Events of Statins - An Informal Internet-based Study

Since statins cause toxins it is equivalent to the premise: toxins are safe. Obviously False.

• Levels of statin dosages today are higher than the studies that qualified them as safe.
• Over 15,000 user reports of statin adverse reactions on only two websites. [Golomb and Graveline, see below]
• Doctors consistently fail to report statin drug reactions.
• Government statistics show too low levels of adverse problems, a reason for inaction.

• Dietary intake of cholesterol has little effect on serum cholesterol.

We make the proper cholesterol we need in the liver, if we do not block the process.

• Mortality is higher with low cholesterol values; below a minimum level becomes unsafe. [The above study shows this]
• MRFIT Percentages who did not die from heart attack: [1% improvement]

Highest cholesterol group 98.7%.

Lowest cholesterol group 99.7%.

• Current goals may be set too low: 330 mg may be a safe upper limit, but to achieve a 1% difference?
• Beware: Cholesterol levels may fall to unsafe ranges leading to myopathy (and neuropathy?).

Statins are not a safe way to lower cholesterol because:

• Synthesis of other essential molecules are blocked. Cholesterol is also essential.

Heme A, ubiquinol, Dolichols, Prenylated proteins.

Oxides are increased: ROS and NOS are raised.

· Natural mitochondrial antioxidants CoQ10 and Heme A will be lacking.

This causes mitochondrial DNA changes and dysfunctions.

This advances aging.

Mitochondrial dysfunctions causal factor in adverse vaccine reactions.

Toxic lipid oxides are formed (rancid fats).

Cholesterol oxides are formed.

• Cholesterol oxides are neuro-toxic. Most likely cause of neuropathy.
• The toxic damage caused by statins is not reversible in about 50% of the cases.

KFP Hypothesis/Prediction: The cholesterol goal is set to an unsafe level

If there is a predisposition for a mental/neural dysfunction (ALS/Alzheimer’s/Parkinson’s) then statins will accelerate symptoms.

Serious questions that should not be ignored:

• What are statins effects on the neurological system? Harmful ones it would seem.
• Are the dietary co-administration of CoQ10 Safety guidelines from the patent being taught and used? No.
• Is cholesterol needed for the production/protection of myelin? Yes.
• Do cholesterol oxides poison nerves? Yes.
• Block biosynthesis of cholesterol and you also block: Dolichols, Prenylated Proteins, Ubiquinone = CoQ10, Heme A .
• Can the body function without these substances or when they have been reduced? Not well.

1. Heme A is essential for mitochondrial energy flow in the cells. Antioxidant: Protects against DNA damage.
2. CoQ10 is essential for mitochondrial energy flow in the cells. It is also an antioxidant.
3. If 1 & 2 are missing or too low we have mitochondrial dysfunction, muscle pain, neural dysfunctions, and atrophies.
4. If 1 &2 are too low we have DNA damage leading to cell death or replication errors. Ageing is advanced; vitamin C helps.
5. What are the functions of: a) Dolichols, b) Prenylated Proteins? Google them to see.
6. What are the various harms of 5 a) & 5 b) being too low. Google to see.
7. We explore the harmful functional effects of low cholesterol and low ubiquinone (CoQ10) in the following pages.

• Why is a high fat, low carbohydrate diet less healthy than a low fat high carbohydrate diet? It is not.
• Why are we promoting the more unhealthy balance between carbohydrates and fats? We are ignorant and need to change this.
• Why are we slandering tropical saturated fats that contain essential fat molecules that are the feedstock for functionally bioactive molecules, enzymes and hormones? Our model is too simple, defective and supported by US Agriculture Dept and farm lobby’s unscientific promotional advertising.
• Why are we not using Pauling’s dietary solution to heart disease? It does not support a multi- billion-dollar Drug/Medical industry.
• Can we afford to support billions of $’s of waste every year we fail to cure heart disease? No. We should use Pauling’s method.

What the Patent tells us:

The Lipitor patent describes the need for high levels [> 300 mg /day] of CoQ10 to be co-administered with Lipitor to avoid harm.

Medical practitioners are not told to do this so they almost universally do not treat the patient properly.

The result is higher rates of side effects than were shown in the earlier lower-dosage-level published studies.

Dr. Mercola: Summary of Key Ideas Presented.

· The odds are greater than 100 to 1 that if you're taking a statin, you don't really need it.

· Cholesterol is NOT the cause of heart disease. Scurvy is the cause. Cure is Ascorbic acid, Vitamins, CoQ10, Lysine, Proline, See Pauling

· Your body NEEDS cholesterol—it is important in the production of cell membranes, hormones, vitamin D and bile acids that help you to digest fat. Cholesterol also helps your brain form memories and is vital to your neurological function.

· There is also strong evidence that having too little cholesterol INCREASES your risk for cancer, memory loss, Parkinson's disease, hormonal imbalances, stroke, depression, suicide, and violent behavior.

· [If you already have these problems you should not take statins. Should not lower cholesterol. Take Lovaza and see if it helps.]

· The ONLY subgroup that benefits from statins has a genetic defect called familial hypercholesterolemia, that makes them resistant to traditional ways to normalizing cholesterol.”

· If you take statins, you MUST take CoQ10 and supplemental high levels of vitamin C.

· Preferred CoQ10 form is ubiquinol. [CoQ10 amount is >200 milligrams per day, if on statins]

· Current Cholesterol levels goals:

· >330-milligram start to worry

· <130-milligram was healthy

· <100-milligram new limit

· <70-milligram for high risk factor cases

· [Seeking a lower level causes statin prescriptions to rise. The drug sales are more profitable]

· Better ways to lower cholesterol than taking statins if you must lower it.

· Eliminate/reduce refined grains & sugars

· Take omega-3 EPA&DHA, krill oil or fish oil.

· Additional suggestions:

· Take CoQ10 as you age, take more.

· Take more vitamin C

· Lovaza: EPA&DHA ethyl esters of Omega-3 oils is a prescription form of EPA & DHA from fish oil.

· One report of significant rapid recovery of mental acuity and speed functions was found.

· EPA & DHA lowers very high triglycerides (fats) in blood without causing oxidizing stress.

· Treatment with LOVAZA has not been shown to prevent heart attacks or strokes.

[insert] = KFP comments or insertion of related information.

Statins Side effects: changes cholesterol balance, low Ascorbic Acid (AA), and CoQ-10 starvation. [oxides proliferate]

Low/oxidized cholesterol harms myelin sheaths of nerves, systemically.

· Systemic energy lowered; Chronic fatigue symptoms worse.

· Does not stop heart and circulatory damage; Post mortem plaques much worse than for those not taking statins.

· Mitochondrial DNA damage and dysfunctions; increases sensitivity to vaccine adverse effects.

· Immune system (T-cell) dysfunctions result increased re-activation of chronic persistent parasitic microbes (bacteria, yeasts, viruses, protozoa).

· Cataracts and other low vitamin C effects due to AA depletion and borderline scurvy. AA consumption is much higher.

· COPD worsens long term [interstitial pneumonitis]; Chronic respiratory irritation and distress, dry cough; Respiratory infections surge from T-cell suppression. Symptoms regress or stabilize on cessation of statins. Lots of questionable media statistical propaganda to the contrary.

· Low-cholesterol dysfunctions: sex hormone production, hair loss, sleep problems, or improper brain and nerve functions.

· Muscle pains, weakness and atrophy (Rhabdomyolysis); loss of endurance, balance problems. Very high incidence of myopathy symptoms

· Muscle and nerve pains cause less exercise, weight gain, less lymph flow and related pathologies.

· Pancreas or liver dysfunction; including a potential increase in harmful liver enzymes; liver toxicity; enzyme test shows destruction.

· Kidney functions impaired; Osteoporosis/bone health worsening.

· Acidosis; Anemia; Sexual dysfunctions. CoQ10 low-level linkage.

· ALS like symptoms due to low systemic cholesterol; Study: remarkable increase in ALS symptoms and diagnostic frequency.

· Memory functions lost: Short-term forgetfulness, lack of focus, mental slowness; brain fog, loss of attention.

· Increased suicide rates; “bad thoughts”; depression; aggression.

· Parkinson’s symptoms start/increase; Alzheimer’s mental decline accelerates.

· Sudden total loss of recent memory [TGA] transient global amnesia. [very rare, but significantly higher in study]

· Heart functions lessened; too low blood pressure; less blood flow to brain, muscles and kidneys.

Low CoQ-10 leads to high aging rates of all cell types:

Dr Graveline: Duane Graveline, MD, MPH See my books: The Dark Side of Statins & The Statin Damage Crisis.

• One cannot reduce cholesterol by the use of statins without simultaneously blocking these other biochemicals sharing the mevalonate pathway.
• Statin drug side effects such as neuropathy and myopathy persist regardless of CoQ10 supplementation levels.
• Excessive CoQ10 inhibition results in free radical (ROS&RNS) increase à Leads to

1. Mitochondrial DNA damage and mutation, primary factors in how we age.

2. ROS and NOS in the presence of low ascorbic acid levels causes scurvy.

3. Resulting in systemic degeneration and atrophies in muscles and nerves.

See John Ely’s papers: John Ely: Coq10 Update JOM5.html John Ely Science of Essential Nutrition CoQ10 and Ascorbic Acid and “Unprofitable Modalities”

References:

· Statin Effects Study, headed by Dr. Golomb of the University of California, San Diego, 4,000 reports of cognitive dysfunction—were diagnosed as rapidly progressing Alzheimer’s disease. Much on too low cholesterol vs. brain functions.

• Dr. Graveline His Web site, www.spacedoc.com , and message board contain nearly 10,000 accounts of statin damage, plus a plethora of information on the adverse effects of these drugs.

· http://www.virginiahopkinstestkits.com/whitakerstatins.html [The] “brain contains an abundance of cholesterol, much of it in the myelin sheaths that insulate the neurons and speed up nerve conduction. Recent research reveals that cholesterol is also required for the formation of synapses, the areas between neurons where nerve impulses are transmitted and received. In fact, cholesterol is so important that it is manufactured by the glial cells in the supportive tissues of the brain.

· Dr Whitaker: No studies show benefits for women. The largest randomized clinical trial of statins in women found Lipitor group had 10 percent more heart attacks than placebo. No research showing any extended life for anyone over age 70.

• UofWashington: Ely: Hyperglycemia Epidemic B6, CoQ10, Mg, Brewers Yeast Homocystine toxicity.
• L. Pauling: Lysine/Ascorbate-Related Amelioration of Angina (Arterial Sclerosis) [JOM 1991] Remarkable case history recovery from arterial sclerosis and heart disease through nutrition. AA+ Lysine àcarnitine. Excellent biochemical analysis of the functional medicine involved.

· TownsendLetter.com/Klenner/KlennerProtocol_forMS.pdf Sclerosis: Multiple Sclerosis MS and Myasthenia Gravis. How to re-grow neural functionality via nutrition. B vitamin dependency high needs. Good discussion on energy reactions.

Dr Whitaker’s Recommendations:

• If you are taking a cholesterol-lowering statin drug, discuss this information with your physician—or find one who is willing to by visiting acam.org or calling (888) 439-6891. To schedule an appointment at the Whitaker Wellness Institute, Newport Beach, CA, call (800) 488-1500 or visit whitakerwellness.com.
• See Dr. Graveline’s books, Lipitor, Thief of Memory, available at amazon.com, and Statin Drugs Side Effects, sold at spacedoc.net. To order CDs of Dr. Whitaker’s interviews with Dr. Golomb and Dr. Graveline, visit healthytalkradio.com.
• If you or someone you know has had an adverse reaction to a statin drug, report it on statineffects.com and spacedoc.net.
• To learn more about safe, natural therapies for preventing and treating heart disease, read Reversing Heart Disease, available at (800) 810-6655, or visit the Subscriber Center at drwhitaker.com.

Dr Whitaker’s References

• Elias PK et al. Serum cholesterol and cognitive performance in the Framingham Heart Study. Psychosomatic Med. 2005 Jan-Feb;67(1):24–30.
• Golomb BA. Impact of statin adverse events in the elderly. Expert Opinion Drug Safety. 2005;4(3):389–397.
• Muldoon MF et al. Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults. Am J Med. 2004;117(11):823–829.
• Pfrieger FW. Role of cholesterol in synapse formation and function. Biochim Biophys Acta. 2003 Mar 10;1610(2):271–280.
• Physicians’ Desk Reference, 61st Edition. Montvale, NJ: Thompson PDR; 2007. Statins side effects.

Important Overview of the Harmful Statin Biochemistry and Increased Nutrient Needs:

CoQ10 and Statins: The Vitamin C Connection by Owen R. Fonorow � 2003

We are now in a position to witness the unfolding of the greatest medical tragedy of all time -  never before in history has the medical establishment knowingly created a life threatening nutrient deficiency in millions of otherwise healthy people. --Peter H. Langsjoen, MD

The following claim from one … 1990 Merck patent (4,933,165) is to add CoQ10 to statin drugs in order to overcome statin induced myopathy: [Not to mention all the various neuropathies]

“1. A pharmaceutical composition comprising a pharmaceutical carrier and an effective antihypercholesterolemic amount of an HMG-CoA reductase inhibitor and an amount of Coenzyme Q.sub.10 [CoQ10] effective to counteract HMG-CoA reductase inhibitor-associated skeletal muscle myopathy.”

[And all the other harm caused by low blood level CoQ10 caused, see the above list of “Side Effects:”]

Fonorow Quote:

“This invention has never been [properly] implemented, probably because the entire world supply of CoQ10 is limited and current production would only supply one-sixth of the world’s statin users.”

Scientific American:

"It's Not Dementia, It's Your Heart Medication: Cholesterol Drugs and Memory"

Two readers’ comments are notable: 

1) Lovaza: DHA&EPA ethyl esters of Omega-3 oils aids recovery of mental acuity & speed.

2) Statin Side effects of HMG-CoA reductase inhibitors in the mevalonate pathway:

o Empirically speaking, HMG-CoA reductase inhibitors (statins) are creating a problem for many of the people taking them. In a recent informal internet-based collection of self-reported data, from the users of statins or their caretakers, the incidence of Amyotrophic Lateral Sclerosis aka motor neuron disease (Lou Gehrig's disease) and other significant major neurological disturbances was remarkable.

o The incidence of ALS is put at 1:200,000 people in the USA and in 351 reports there were 19 reports of ALS/MND. On the current incidence statistics, I should have seen more than 3.6 million reports before seeing 19 cases of ALS.

o Interested parties can read the informal report (published by the journal of independent medical research) and see precisely what information which was self-reported; at the following URL: http://www.joimr.org/JOIMR_Vol7_No1_Dec2009.pdf

o There were a further 8 cases of Parkinson's disease and single occurrences of CIDP, Alzheimer's disease, and Progressive supra-nuclear palsy. In all, there were 29 reports of major progressive neurological dysfunction. [29 out of 351]

KFP: Flawed Statistical Marketing Studies vs. Anecdotal

More than 14,000 patient reports were collected on web, vastly more than the number of doctors’ adverse drug reports. Patients report their doctors deny any chance of harm from statins and refuse to link their own side effects to statin drugs. Doctors appear brainwashed by all the positive ‘educational’ propaganda planted by the drug makers. The aggregation of so many similar anecdotal reports of harm belies the earlier low dosage statistical studies. Also, the known biochemistry proves multiple functional mechanisms of harm. Functional mechanisms should trump statistical propaganda. However control of funding decides what the doctors hear. The doctors are the target of the propaganda.

Many persons reported adverse symptoms on starting statins and/or reversal of some symptoms when quickly stopping statins. The biochemistry basis for the functional science is documented. If CoQ10 levels are too low, functional changes, some irreversible, lead to loss of functionality of muscles, nerves, brain functions. High levels of ascorbic acid (AA) can partly reduce the problems resulting from low CoQ10 levels. But the amounts and frequency of AA intake (10 to 20 grams/day, 12x/day) almost always are not at the levels needed to provide protection from statin dosages (10mg or more per day). CoQ10 supplementation helps but there is the essential Heme A deficiency that no one is addressing, that is also critical.

Pharmacokenetics of AA has the blood half-life time as ½ hour. This means the AA concentration will be 1/8 in 1.5 hours; 1/64 in 3hours; 1/2¹² after 6 hours. Under statin-caused chemical stress and increased ROS/NOS the amount of AA per day may well exceed 24 grams. This is 2 grams every 2 hours. Not much if you think of AA as a food that is metabolized and quickly excreted. Some terminal conditions need 150 grams/day/100kg body weight by IV to achieve remission. Plasma concentrations need to reach the same levels that are lethal to microbes/cancer-cells in-vitro. See Cathcart: Titration to Bowel Tolerance

Many of the symptoms of the statin reactions are the same as ageing, so they are dismissed as having no proximate cause. Functional causes are multiply documented in the literature, but most are unread. See John Ely’s wisdom. UofWashington: Ely: On the Science of Essential Nutrients 2002 “Unprofitable Modalities”

Promotional statistical medicine studies are substituted for functional, biochemical science. Study reports are subject to editorial distortions that do frequently occur, because they are drug-company funded. Study or publications about adverse issues are not funded, published or promoted.

A Well-Documented Analysis of 351 Statin Case Histories:

Adverse Events of Statins - An Informal Internet-based Study The whole study is on the web as a PDF.

This is a well-documented analysis of a body of 351 case histories that show similar patterns of pathological conditions.

• It showed that most clinicians were dismissive of patients’ conclusion that symptoms were side effects of statins.
• It showed that clinicians did not know that taking statins raises death rates.
• It showed lack of knowledge by the clinicians of the functional biochemical disruptions that statins cause.
• It showed ignorance of need to increase CoQ10 to avoid myopathy and neuropathy.
• Only 11 of 351 cases had been prescribed carnitine or CoQ10 during recovery
• About half of the side effects were permanent, but progression stopped when taking statins stopped.

Abstract:

This report was the result of gathering and collating information from self-reported accounts of adverse reactions to HMG-CoA reductase inhibitors.

The information was gathered from 351 patients who had signed an e-petition that will be sent to the World Health Organization.

Every patient reported adverse reactions to statins and:

• 61% of the patients had reported they stopped taking the statins because the side effects were too severe to persist with the treatment.
• 63 patients reported they had sustained permanent damage and
• 120 people were still experiencing unresolved adverse reactions.
• 18 cases of amyotrophic lateral sclerosis/motor neurone disease diagnosed, with
• One case of ALS being diagnosed within six weeks of starting statin therapy.
• 69 patients experienced memory loss and
• 18 patients complained of cognitive impairment, while
• 6 patients experienced transient global amnesia [total memory loss].
• 29 instances of major neurodegenerative disorders including
• Parkinson’s disease,
• Alzheimer’s disease,
• multiple system atrophy,
• progressive supra-nuclear polyneuropathy,
• chronic inflammatory demyelinating polyneuropathy and
• amyotrophic lateral sclerosis/motor neurone disease.

Additional items for inclusion were

• non-productive cough,
• deterioration in general health,
• fatigue,
• weight loss,
• fever and
• dyspnoea.

Reported Neuropathies: From Adverse Events Study (above) 351 reports.

The respondents’ complaints about symptoms were often localized to one or two limbs or several digits. Report numbers: muscle spasm/cramp/ fasciculation (30); neuropathy (24); parasthesia (16); visual disturbance (12); neuralgia (11); neurological damage (9); Slurred speech (8); auditory disturbance (7); Tremor (3); dysphagia (1);.

Increased Statin Caused Deaths and Serious Disorders: From Adverse Events Study (above)

6 of 351 deaths

17 of 351 near death

18 of 351 ALS symptoms induced

29 of 351 serious neurodegenerative disorders

40 of 351 mobility issues/problems

295 of 351 myopathy symptoms

Other websites have collected over 14,000 adverse cases.

Estimated 15 million patients treated. Rate of harm is .1% or likely several times higher than these web results.

The update concluded by stating that there was “sufficient evidence to support a causal relationship” between statins and the newly acknowledged adverse reactions.

In the UK, the information was related to the latest instruction from the Medical & Health Products Regulatory Agency where adjustments to the patient information leaflet for statins and a change in the

information given to patients by their treating clinicians is now mandatory.

Lipitor Side Effects Response to a Web Inquiry:

http://www.medications.com/lipitor/lipitor-side-effects

“I am a 56-year-old male who has been relatively good health. I have been taking Lipitor 10 mg three times a week for approximately 8 years with excellent cholesterol results.

I have been noticing more lower-leg discomfort/pain over the last couple years, and particularly numbness/tingling in my feet this past year. I had been running 12-16 miles each week up to the lst year and have had to cut back on this because of the heavy sensation in lower legs and also some osteoarthritis which has been developing over the last 20 years.

My Lipitor dose was increased to 10 mg daily last year after my brother died suddenly from a cardiac event and my family history suggested it might be warranted to increase the dose, but after 3 months I couldn't stand the extra pain, so cut back to 3 days a week.

I still am bothered with these symptoms but not to the same degree. Should I stop all together?”

Reply Dave847 - Adverse Side Effects of Statin Cholesterol Lowering Drugs The following headlines from HEALTHFREEDOMNEWS reveal the many little-known side effects of the artificial statin drugs, some of which are required to be reported in Canadian statin drug ads, but not the U.S. versions.

[From: CoQ10 and Statins: The Vitamin C Connection by Owen R. Fonorow, 2003]

Statin Cholesterol Lowering Drugs have the following characteristics:

· They deplete the ubiquinone (vitamin-like) Coenzyme Q10 causing cardiomyopathy and heart failure.

· They change, weaken, damage, or destroy muscle (depending on dose and concomitant use of other drugs).

· They do not slow atherosclerosis.

· They make atherosclerosis worse (scurvy is induced).

· They increase AA burn-rate; AA intake needs are increased.

· They increase allergic sensitivities.

· They complicate COPD, chronic dry cough.

· They induce sudden total memory loss.

· They increase eye cataract risk.

· They suppress immune function.

· They are linked to cancer.

· They have been linked for ten years with Rhabdomyolysis and Myoglobinuria.

· They have been linked with elevated transaminase (indicator of liver and kidney damage).

· They are linked to nerve damage.

· They slow mental functions and decrease focus.

· They induce muscle pain, and cause muscles to atrophy.

· They do not extend life.

· They increase serum Lp(a) concentrations (increasing odds of heart attack or stroke up to 70%).

· They reduce left ventricular function.

· They elevate the lactate to pyruvate ratio.

· They enhance LDL cholesterol oxidation.

· They interfere with any function that depends on cholesterol or CoQ10 or vitamin C. (e.g., sex hormone production, hair growth, sleep, or proper brain and nerve function)

· They are prescribed to 13 million (in the U.S., 25 million worldwide) creating a $20 billion market.

· They will cause 65,000 predicted new myopathies per year. [USA?/World?]

Defenses against Statins side effects:

Supplemental Vitamin C and CoQ10 are completely nontoxic and would lessen or eliminate most of these statin-induced effects.

However if enough of the right kind of cholesterol is not maintained, the neural effects will be neuropathies and myelin sheath dysfunctions.

More headlines from BOLENREPORT.COM illustrate the health benefits of Vitamin C:

· Harvard: Vitamin C Only 1 of 880 Substances to Regenerate Heart Muscle From Stem Cells.

· Fifteen-Year Harvard Study of 85,000 Finds Single Vitamin C Pill Reduces Heart Disease Almost 30%.

· Linus Pauling Angina and Heart myopathy reversed: With Vitamin C+Lysine+Proline+vitamins+CoQ10

· The Risk Of Stroke Was 70% Higher Among Those in the Lowest Quartile for Serum Vitamin C Than Among Those in the Highest.

· Vitamin C heals atherosclerosis.

· Vitamin C Inhibits Lipid Oxidation in Human HDL.

· More Vitamin C as Pills Reduce Cataracts by 77%.

· High-Dose Vitamin C Completely Prevented Drug-Induced Amnesia in Mice.

· Carnitine, Its Building Blocks Vitamin C and Lysine, Increase Muscle Strength.

· Matthias Rath Claims Cancer Halted With Vitamin C+Lysine+Proline and EGCG (Green Tea Extract).

· Vitamin C Boosts Immune System in as Little as 5 Hours (NIH).

· Vitamin C Pills Extend Life 6-Years (USC).

· Vitamin C (and Lysine) Halt Atherosclerosis

· IV Vitamin C Reverses Endothelial Dysfunction.

· Vitamin C neutralizes many toxins, including toxic shock.

· Vitamin C acts as an antihistamine in suppressing asthma and allergies.

· Vitamin C neutralizes oxides ROS & NOS

· Vitamin C increases blood oxygen transport.

· Vitamin C helps mitochondria to recover from toxic dysfunctions

· Vitamin C chelates metals, especially toxic aluminum an adjuvant in vaccines.

· Vitamin C - New Treatment for Osteoporosis.

· Vitamin C Can:

1. Prevent the Deterioration of Heart Blood Vessels, Completely; and

2. Cure Even Large Aortic Aneurysms (with L-lysine & L-proline) Without Surgery.

CoQ10 and Statins: The Vitamin C Connection by Owen R. Fonorow � 2003

Conclusions [with KFP comments]

· Apparently a $20 billion market has blinded some scientists. Merck and other pharmaceutical companies have known about the CoQ10 biosynthesis issue for more than a decade. (Few medical doctors in the U.S. are aware of this problem, or how serious it can be without the proper nutritional changes)

· No theory exists to justify the use of statin drugs. This author has seen no data or evidence that demonstrates any real health benefit for statin drug use that overcomes the proven detriment of hampering the production of CoQ10.

· One has to ask how the FDA approved the existing claims for the statin drugs. Apparently the dosage of a statin is important. [Too high a dosage causes significant harm. The biochemistry of the harm is documented but ignored by the regulators, who rely on outdated and flawed low dosage statistical reports]

· [Dosages have increased from the low levels of the original safety testing. Current dosages have much increased harmful effects, because they lower CoQ10 blood levels so much, and lead to increased ROS&NOS levels in the mitochondria, DNA damage, mitochondrial dysfunction]

· At lower dosages, the "bad" effects are reduced so that the mortality curves between the control and statin groups are similar. The studies rarely try to quantify muscular aches and pains and, instead, usually focus on lowered cholesterol as the end-point.

· Ergo, if the drug lowers cholesterol, beneficial effects on heart patients are assumed.

· [Harmful effects are dismissed. Like: without the antioxidants, oxides of the lipids form and cholesterol oxides are neurotoxins]

According to Dr. Langsjoen,

· In my practice of 17 years in Tyler, Texas, I have seen a frightening increase in heart failure secondary to statin usage: statin cardiomyopathy.

· Over the past five years, statins have become more potent, have been prescribed in higher dosages, and have been used with reckless abandon in the elderly and in patients with [near] normal cholesterol levels. [Without CoQ10 & vitamin C supplementation]

· We are in the midst of a congestive heart failure epidemic in the U.S., with a dramatic increase over the past decade. [Statins do not work]

· Are we causing this epidemic through our zealous use of statins? In large part, I think the answer is yes.

Postulation:

No human who consistently consumes 10,000 mg or more Ascorbic Acid (vitamin C) and 300 mg or more of ubiquinone (CoQ10) daily has heart disease. [Add L-Lysine and L-Proline for more effectiveness according to Pauling and Rath]

Predictions:

· Studies that purport to show that statins benefit heart patients either have mischaracterized the data or, eventually, will be shown to be fraudulent, marketing propaganda. [Look into the pseudo science of Dr Ancel Keys, a discredited fraudster.]

· We defy any researcher to find a contrary example to our postulation, and we stand by the prediction.

· Cardiologists, as a rule, are highly trained professionals, yet they are being duped by drug company efforts to expand markets. They love these statin drugs, and why not? Patients keep coming back.

Conclusions:

· Nonetheless, we find it unconscionable that editors of mainstream medical journals, along with representatives of the U. S. government and the news media, continue to hide the explosive research results on vitamin C and CoQ10 from U.S. doctors.

· We are now in a position to witness the unfolding of the greatest medical tragedy of all time—never before in history has the medical establishment knowingly created a life threatening nutrient deficiency in millions of otherwise healthy people.

· Disregarding malpractice, the continuance of ignoring vitamin C and CoQ10, while marketing and prescribing statin drugs for heart patients is criminal.

--Peter H. Langsjoen, MD

KFP Conclusions:

So the companies failed to educate doctors in the proper combined statin & CoQ10 & Ascorbic Acid dosages, resulting in a lot of uncontrolled ROS and NOS with side effects, cholesterol poisoning by oxidation, causing mitochondrial dysfunction, immune T-cell dysfunctions, and increased susceptibility to vaccine side effects causing neurological harm. Since AA is depleted, scurvy threshold is worsened and aging is speeded up.

Except for the Medicare costs of treating the increased symptoms, the billions of dollars in savings in the SSI retirement costs due to earlier deaths would be welcome to a government that is unable or unwilling to repay the tax dollars borrowed from the SSI trust fund.

Now the CDC and the FDA have recognized that the combination of mitochondrial dysfunction (or existing ROS/NOS) and some vaccines (Flu, HiB, DPT, MMR, HPV) can lead to Autism and ASD neural atrophy. For older persons this dysfunction shows as fatigue. The Flu vaccine can cause an adverse reaction when the accumulated microbial parasite load is high enough. The FDA has a table on their website that indicates that vaccination should not be administered if the patient feels unwell, or if various immune cells are compromised. The table remains unused because there is no practical way suggested to quickly test for this. Suggestion: Find a test that would work and use it. SED rate?

Too many clinicians do not understand how critical the scurvy state is to health and how quickly (1-2 hours) borderline can become critical to survival. They assume scurvy does not exist today and cannot recognize it. The depleted AA state coincident with vaccination causes adverse events that are well documented elsewhere on the web. See Kalokerinos, Klenner, and Cathcart, Stone. The pharmacokenetics (1/2 hour, blood serum AA half-life is remarkable, almost unbelievable. But its consequences, when understood, lead to validation of a new unprofitable treatment modality (AA, CoQ10, Lysine, Proline) that is extremely effective and low cost. So effective that it is considered a threat to the entire medical delivery system. It is up to the smart ones to find a way to make it generally available in all its modalities, not to suppress it.

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