COPD and Anti Infection Countermeasures: COPDcountermeasures.htm


1.     COPD Introduction:

2.      Cystic Fibrosis Lung Dysfunctions

3.     Specific Colonizing Microbes: Having a respiratory component

4.     Fungus/Yeasts/Molds Immune suppressing and respiratory inflaming

5.     Persistent Viruses Suppressing/exciting immune system, cofactors in inflammation flares.

6.     Research related to the herpes viruses causing diseases:

7.     Table 1 Human Herpesvirus Variants, Attributes, and Relationships

8.     Respiratory Infection Bacteria List including many pathogens

9.     Nutrition Factors: Tropical saturated fats

10.  Gut Inflammation Infections  Many gut inflammations start as respiratory infections

11.  COPD  Treatments using diet changes, enzymes, and POPG aerosol.

12.  20 Specific Recommendations:  Oils, Honey, Vitamin C, Serrapeptase, etc.

13.  Table 2 of Antibiotics Vs. Pulmonary Microbes:

14.  Dr Frederick Klenner: (1953) Early Clinical Usage of Vitamin C.  Quote: Case history of rapid recovery

15.  References:  Tropic Oils, POPG, Klenner on Vitamin C

16.  References to our website content: Summaries and notes from our Ongoing Research



COPD is a chronic inflammation of the respiratory tract with some swelling which reduces the ease of breathing and lung function.  It has a polymicrobial multi-factored cause with various components shifting to an acute stage at times.  The microbes involved colonize epithelial airways surface lining cells and can invade immune cells sent to kill/eat them.  The microbe colonies may have protective barriers that limit the transfer of antibiotics into the colony. Proteolytic enzymes like serrapeptase can wipe out the barriers, permit antibiotics to pass inside the colony, and reduce or wipe out the colonies.

The established colonizing microbes form a microbiome that brings many diverse genetic recipes, that colonize our cells and, which changes our cells intrinsic chemical activities.  Target cells that are colonized by multiple microbes. This makes analysis of the resultant effects, (positive and negative) hard to sort out.  Genetic decoding of the microbes RNA/DNA, including differences between microbe strains, are providing new clues. Research is now describing how the invaders can influence our cellular immune activities, molecule making and molecule using in our chemical pathways.

COPD is caused by a persistent microbiome, which is sensitive to antimicrobial, nutritional, and enzyme therapies.  The following discussion identifies some of the troublemakers and some of the methods of reducing the colony produced pathogenicity.


Cystic Fibrosis Lung Dysfunctions

Cystic Fibrosis (CF) is a respiratory disability similar to COPD, which has a genetic cause. It is characterized by failure of hydration of the epithelial cells of the respiratory tract and lungs.  Infections play a part in the progressive loss of breathing capacity.  Bacteria Pseudomonas aeruginosa colonizes many CF sufferers. It forms an antibiotic-resistant biofilm in the lungs. Research shows for in a healthy mouse, glutathione levels in the lungs can naturally rise 3x to prevent the bacteria from colonizing.  In the CF model there is no increase of glutathione. Vitamin C in high blood levels regenerates oxidized glutathione.

Treatments include doxycycline to control the infection components.   Liposomal AA (L-AA), which is vitamin C (or alternatively sodium ascorbate) nano-coated with lecithin and homogenized using ultrasound.  L-AA has improved outcomes for CF with better pharmacokinetics compared with AA.  98% of the encapsulated AA transfers to the blood and blood, >5 times more than water soluble AA.   With L-AA, blood AA levels higher than for AA IV have been produced. See L-AA discussion.  L-AA, 5 grams 2 x per day, has produced progressive improvement of reduced lung capacity from ~ 50% to over 85%.

L-AA is available on in multiple forms.  Other lipids --- Vitamin E, CoQ10, and possibly coconut/palm/olive oils containing fatty palmitic and lauric acids may in future be used to enhance antimicrobial actions.  Quercetin has been suggested as a possible Liposomal additive for cystic fibrosis.  Vitamin C Foundation has recent blogs showing recovery of lung functions. This URL contains a large list of research hot links to sites relating AA and cystic fibrosis treatments.  Since L-AA works when combined with tetracycline antibiotics for Cystic Fibrosis and its infections, it should also improve COPD lung functions using similar combined multifactorial treatments. How AA Works


Specific colonizing microbes having a respiratory component

Microbes likely to cause or contribute to COPD are:  Fungus/Yeasts/Molds, Viruses, Bacteria

Fungus/Yeasts/Molds: Saccharomyces cerevisiae, Candida albicans(?%) systemic infections; Penicillium marneffei and Aspergillus fumigatus. Spread by spores; pathogenicity depends on immune suppression, also suppresses immune system.

Mostly RNA Respiratory Viruses, (incidence%): Picornaviruses, tiny RNA( 36%), Enteroviruses including Coxsackie A & B viruses targeting the gut epithelial cells; Paramyxoviridae, RNA, PIV1-4, RSV, Respiratory Syncytial Virus  (22%), RNA; Adenoviruses: 3,4,7,14 (10%), DNA; Influenza A (25%) RNA; Rare respiratory SARS coronavirus large RNA; Rare respiratory onset, UTI tropic, RNA Hantavirus.


Persistent Viruses, suppressing/exciting immune system, cofactors in inflammation flares.

HHVs suppress MHC I & MHC II: 

Human Herpes Viruses 1-9:

HSV-1&2, Herpes simplex 1&2;

HHV-3, Varicella, chicken pox;

HHV-4, Epstein Barr virus, EBV;

HHV-5, Cytomegalovirus, CMV blocks inflammatory cytokines;

HHV 6&7, Roseoloviruses, Roseola infantum, fatal encephalitis and persistent immune hypersensitivity

HHV-8, Kaposi’s sarcoma.


HHVs 6&7 can cause a fatal encephalitis. Could certain strains cause a nonfatal encephalitis and/or a drug/vaccine immune hypersensitivity and ASD inflammations?  There is some evidence for this.  HHV7 incidence is estimated to be 90%. Acute infection stage is in infancy when vaccinations take place.  Many HHV6 and HHV7 infections have minimal symptomology. This hypothesis needs more investigation.


Research related to the herpes viruses causing diseases:

The co conditions include:  Alzheimer's disease, atherosclerosis, cholangiocarcinoma, Crohn's disease, chronic fatigue syndrome, dysautonomia, fibromyalgia, Irritable bowel syndrome, multiple sclerosis, labile hypertension, lupus, pancreatic cancer, pancreatitis, pityriasis rosea, Type II Diabetes Links are to Wikipedia definitions.

Less well studied Herpes simian viruses infect laboratory monkeys used in vaccine research and vaccine production. These simian viruses may be contaminants of human and animal vaccines in both experiments and production. Since tests for the presence of these simian viruses do not exist, or are not used, the possibility of wide spread iatrogenic harm does exist.  Vaccines can contain unintended live viruses or viral components as contaminants or as active agents.  This has happened several times in the past and may happen again in the future.  Infected HIB and Polio vaccines are past examples.


Table 1 Human Herpesvirus Variants






CoVirus that Makes worse



Target & Latent

1 & 2

Herpes Simplex: 

Mouth-1, Genitals-2

HSV 1&2

HSV 50%


Retro Virus meds work

STD: Cold sores, lesions

Alzheimers, Bells Palsy, Neuralgia

Mucus epithelial cells

& Latent in Nerve Cells


Varicella, Herpes Zoster





Retro Virus meds work

Chickenpox, shingles, Lupus (SLE)

Mucus epithelial &

Nerve cells


Epstein Barr virus




Retro Virus meds work

Chronic Fatigue Syndrome, Lupus, Lymphomas

Epithelial &

B immune cells





Turns on Cancer genes

Retro Virus meds work

STD: Mononucleosis, Hepatitis, Heart Disease, sclerotic cofactor

Monocyte, lymphocyte, and epithelial cells


Roseolovirus aka Herpes Lymphotropic virus



HIV in CD4-Tcells

Retro Virus meds work

Sixth disease (roseola infantum)

Multiple sclerosis cofactor with MSRV/HERV-W

CD4+T cells and others TBD, Lymph system epithelial?





HIV in CD4-Tcells

Retro Virus meds work

Sixth disease (roseola infantum)

Recurrant & fatal Encephalitis, Drug induced hypersensitivity

CD4+T cells and nerve cells others (stem cells) TBD


Kaposi’s sarcoma



HIV activates pathogenic modes

Retro Virus meds work

Cancer related to HIV


Lymphocytes &

B immune cells, and more?


Variants of KSHV

HHV9 & 8+


HIV activates pathogenic modes

Retro Virus meds work

HHV-8 pirates gene sequences; it is chimerical

Lymphocytes &

B immune cells, and more?


Respiratory infection bacteria include:

Streptococcus pyrogenes, rheumatic fever, scarlet fever and necrotizing faschiitis;

Staphylococcus Aureus (co infection with cold viruses);

Streptococcus pneumonia (many strains, aka pneumococcus, rheumatic fever);

Mycoplasma pneumonia moves systemically and it causes rheumatoid arthritis;

Other Mycoplasmas: M. fermentans, M. hominis (arthritis), etc;

Ureaplasma, respiratory invasion moves to urinary tract, cystitis;

Chlamydia pneumonia invades RT Epithelial cells and moves system wide, poly-pathologies & highly persistent;

Chlamydia psittaci, Psittacosis, aerosols, reservoir is birds; etc.

Yersinia entercolitica, acute respiratory invasion moves to gut causes IBS & Ankylosing spondylitis;

Mycobacterium Paratuberculosis (milk, Johne’s Disease) moves to gut causes IBS and Crohn’s disease;

Mycobacterium tuberculosis, respiratory TB and System wide infections;

Legionella pneumophila, Legionnaires Disease;

Coxiella burnetii (Milk aerosols, tics), Q-Fever;


 Clostridium difficile flare in the gut is a complicating factor in the gut dysbiosis introduced by the antibiotics used to treat COPD.  It is best treated in a hospital environment; gut dysbiosis in a HMO service model with infrequent doctor attention does not lead to rapid and effective identification and treatment.


Nutrition factors:  Tropical saturated fats

Lack of certain tropical saturated fat precursor components restricts hormone, and/or enzyme action, and also can lead to immune system up disregulation.  Dietary fats propaganda has classified several essential precursor saturated fats as harmful when they are not.  Tropical oils like coconut and palm contain vitamin complexes with additional nutritional values.

Mary Enig described some effects of the U.S. diet: low intake of tropical oils causes susceptibilities to microbes, e.g. HIV, RSV and Mycoplasma pneumonia, Chlamydia pneumonia, etc, which form colonies and invade cells which form a reservoir of microbes that are contributing factors in COPD flares. 

She also has noted neglected papers that report insufficient butter intake in the presence of high amounts of canola oil (Omega3) has lead to heart lesions. Rats died on canola diet with no palmitic acid intake in two tests, one in Japan and one in Canada. Saturated fat molecules are precursor molecules for essential molecules made in the body.  Tropical oils have been given a bum rap. Oils intake needs balance, which is missing. (Refs: 7-12)

Restriction or elimination of essential tropical fat precursors in our diet is contributing to gut and respiratory dysbiosis.  Lauric acid in coconut oil converts to monolaurin (ML) in the gut. ML dissolves gut microbe’s lipid coatings and interferes with their ability to bind to target cells. (Ref: 3)  A surfactant, sodium lauryl sulfate, a common detergent, might play a similar role, but simple monolaurin formed in the gut is the safer alternative.  Sodium lauryl sulfate may be toxic if ingested.

The saturated fats from goats are richer that other sources in Capric, Caproic , and Caprylic.  Caprylic is especially antagonistic to yeast infections.

Palmitic acid, another saturated fat found in butter is also essential as will be discussed in detail in following paragraphs.

Gut Inflammation Infections: HIV/AIDS, Measles/ASD, Yersinia entercolitica/Ankylosing Spondylitis Unk/lower back pain.

HIV recovery or reversal has been multiply reported based on coconut oil and/or vinegar, taken incessantly, as a drug, multiple times a day. MMR live-vaccine sometimes causes chronic measles gut-infection.  Autism (ASD) neural inflammation might be reduced if this infection is eliminated. High amounts of Vitamin A or cod liver oil is antiviral. 

Cleaning out the gut, sterilizing with vinegar and water, Rebooting the gut flora and repopulating gut with probiotics, buttermilk, and yogurt should help by revising the gut ecology. Maintain new ecology with daily coconut and palm oils and refresh probiotics with yogurt cultures and live yogurt cultured sauerkraut. For IBS, a cabbage fermented culture was found to help. See: or find similar products in health stores. Buy one use for starter and make your own fermentation with raw cabbage, lightly blended and yogurt with known cultures. (Ref 17) 

COPD treatment using diet changes, enzymes, and POPG aerosol.

A palm oil derivative, Palmitoyl-oleoyl-phosphatidyl-glycerol (POPG), a phospholipid surfactant, normally found in the lungs, plays a complex beneficial role in binding to respiratory synclinal virus (RSV), to Mycoplasma pneumoniae, and likely to other COPD bacterial components. POPG interferes with the respiratory microbes’ ability to invade epithelial cells, to replicate, and to form plaques/biofilms.  It also interferes with RSV’s ability to attach to molecules that stimulate immune reactivity. (Refs: 1,2)  POPG also reduces the surface tension and viscosity of lung fluid and makes it easier to breathe.

A dietary intake low in palm-derived oils, precursors to POPG, is likely to predispose to COPD, by insufficiently blocking microbial ligand functions. Butter contains lots of palmitic acid and small daily amounts are essential.

20 Specific Recommendations:

1.     Antibiotics are useful for COPD flares.  Tetracyclines, and other antibiotics are useful. See the table below.  Antivirals and anti Retroviral medicines effective against picoRNAviruses may also be helpful. See 4, below. Antibiotics kill microbes causing the release of endotoxins.  This results in a flood of oxides, which oxidize the antioxidant vitamins that are present. (Vitamin A, C, E, and CoQ10) Specifically, vitamin C (A-AA) converts to DHA.  More A-AA must be provided frequently to keep the A-AA/DHA ratio in the healthy range much greater than 1.

2.     Add butter, palm, palm kernel, and coconut oils to the diet in amounts of several tablespoons, total per day. Use these oils in place of oils from peanut, rapeseed = canola, corn, soybeans, cottonseed, etc. Vinegar taken daily has a similar microbe coat-dissolving effect in the gut.  These ingredients can be added appropriately to recipes or taken separately as a supplement. Extra virgin olive oil is antimicrobial, as is olive leaf extract.

3.     Vinegar, raw honey and honeycomb are both antibacterial and anti-inflammatory. Dr D. C. Jarvis in his book Folk Medicine (1958) Chapter 9 details case histories demonstrating the benefits of chewing honeycomb to cure respiratory inflammation.  The combination of a few tablespoons of apple cider vinegar and raw honey in 8 oz water taken 3 times per day, before meals,  reduces high blood pressure and may reduce the pain of sore throat.  Eating a small amount of raw honey may reduce the respiratory irritation and inflammation of COPD and chewing honeycomb or beeswax obtained from natural honey producers is noted by Dr Jarvis to be immediately effective.  Google [honeycomb honey] or ask at your health food store.  Beeswax and honey contain powerful antibiotic molecules with a wide spectrum of antimicrobial effectiveness.  Honey is a good source for potassium and magnesium which may be in too-low systemic levels. Vinegar facilitates calcium mobility in the body.

4.     Iota-Carrageenan nasal spray  Iota-Carrageenan is antiviral against picoRNAviruses which include the rhinoviruses that cause the common cold.  Recently, (2010) a study has proven that a seaweed derived food additive molecule in nasal spray form can reduce inflammation-promoting molecules associated with respiratory distress. “Pro-inflammatory mediators FGF-2, Fractalkine, GRO, G-CSF, IL-8, IL-1α, IP-10, IL-10, and IFN-α2 were reduced in the Iota-Carrageenan [treated] group.”  Various forms of carrageenan have been used in food preparation for hundreds of years in cultures worldwide, from Scotland to China and the Philippine Islands where most of the world supply is made today. Carrageenan also comes from California kelp.  Nasal spray can be prepared from dissolving the powder in sterile water, and before it is jelled, it can be dispensed from a spray bottle, like with an inhaler.  This inexpensive spray costs hundreds of dollars less than the cortisone-based sprays that suppress the immune system without the beneficial antiviral actions that iota-carrageenan provides.  Research is ongoing towards product development.

5.     The enzyme Serapeptase is known to lyse fibrin, to liquefy mucus, and to destroy respiratory bacterial biofilms.  It should be taken as needed to reduce congestion and facilitate breathing. It liquefies phlegm. See our findings on Plaque and Biofilm antibiotic resistance: Serrapeptase description.  Mucinex which contains Guaifenesin operates in a similar manner to lyse mucus and ease breathing.

6.     Ascorbic acid 2-3 grams every 2 hours 12x /day for 4 days has controlled/eradicated wild measles infections. (Klenner-13)  The same high dosage and intake rates may suppress viral respiratory infections. Ascorbic acid improves blood oxygen transport. AA along with CoQ10 (>30 milligrams per day) work together to support cellular metabolism, boosting available energy to the heart, brain and muscles.  The AA molecule disables hyaluronidase, an enzyme produced by pathogenic bacteria that use it as a spreading factor to dissolve tissues containing hyaluronic acid and to increase bacterial mobility.

7.     Use Liposomal AA to produce higher AA blood  levels, similar to a high dosage IV sodium ascorbate treatment. Take oral Liposomal AA (L-AA), about 5-7 grams every two hours.  L-AA will have a transfer efficiency from gut to blood of nearly 98 percent compared to the ~20% for oral AA.  4-5 days of this high dose L-AA should elevate the active AA in the blood to the antimicrobial broad spectrum antiviral killing level.  These same levels are those most effective to kill cancer cells and infected immune cells.  If a Herx reaction, back off or lower dosage levels for a few days and resume, periodically until the toxin load from the microbe die offs decreases to insignificance.  If histamine is generated, antihistamines may be helpful. ARB blockers also help stop the cytokine cascade of microbial die off.

8.     See: Vitamin C (AA) Pharmacokinetics and Pharmacodynamics.  AA is a universal toxin neutralizer molecule that must be ingested like food because it is used up in the process.  Tens of grams per day in dosages every 1-3 hours are needed in severe toxin reactions and for acute infections. Sodium ascorbate is administered by vein infusion (IV) for faster, more complete assimilation.

9.     Gut dysbiosis implies a greater need for vitamins: E.g., Vitamin C, B6, B12, E, and A, See Klenner on Myasthenia Gravis for additional nutrition notes for difficult vitamin dependencies where very high levels of nutrients are required by some patients. Beware mineral deficiencies like magnesium.

10.  Vitamin A from cod liver oil has reversed ASD (see G Alpha protein) for a tunnel-blindness genetically predisposed subpopulation. Megson  Vitamin A is antiviral.

11.  Coconut and palm oils if gently refined contain CoQ10, Vitamin E complex, and Vitamin A complex molecules including multiple variants of Vitamin E’s tocopherols and tocotrienols. This mix is a naturally nutritious feedstock for our chemical pathways to make essential cholesterol molecules including both metabolic and steroid hormones.

12.  Beware statins that block the mevalonate pathway that produces essential cholesterol, HEME and CoQ10, leading to neural and muscular degeneration (Rhabdomyolysis), pain and peripheral neuropathy. Statins reduce vital energy and oxygen transport, leading to systemic degeneration of brain and muscle functions.

13.  Tetracycline antibiotics: Minocycline, Doxycycline, and OxyTetracycline work against Mycoplasma pneumonia and other “atypical pneumonia”  bacteria in COPD. See our book Chapter 2 and see the Road Back Foundation.  Oral antibiotics kill helpful gut bacteria. Reboot the gut microflora using plain yogurt and buttermilk. See note 20 below.

14.  For nutrition websites see references at our website.

15.  For combined AA and other multi factors in a low sugar Ketonic protocol see our website.

16.  See: for help with combined antibiotic protocols (CAP) for persistent Chlamydia pneumonia.

17.  A steam inhalant is an effective technique for treating respiratory bronchitis, catarrh and sinusitis. Mix 30 ml of compound tincture of Benzoin with 2.5 ml eucalyptus oil or T-tree oil, Optionally add: 5 drops peppermint oil, 5 drops lavender oil and 5 drops pine oil (or turpentine). Shake well in a small bottle. Put a teaspoonful in a bowl and pour on 1 pt (500 ml) hot boiled water. Cover the mouth and nose and the bowl with a towel or cloth and gently inhale for a few seconds at a time. Keep the eyes closed and outside the tent. The respiratory blockages will slowly clear and loosen. Repeat as necessary to free up the breathing passages.

18.  Hypothetical future treatment modality: POPG is available as a powder in small amounts (100 milligrams) but is expensive.  It would be needed in micrograms in an inhaler (~50ug/ml) It could be liquefied and packaged in a spray bottle by a compounding pharmacy. This application has not been studied or approved by the FDA.

19.  Hypothetical treatment modality: Make your own Lecithin based Liposomal AA and add  coconut, palm, vitamin A, Vitamin E, and Vitamin C to the blend mix.

20.  Blend raw sunflower seeds and add to no sugar plain yogurt, plus ice, plus frozen berries, sugar free vanilla extract, and Xylitol for sweetening. Xylitol is a sweetener that is strongly anti-yeast and it poisons sugar-loving microbes forcing them to gene shift and mutate away from using the sugars in HFCS (corn sugar). It has an anti plaque effect in the mouth and there are papers showing Xylitol also forces a microbiome shift in the plaques and biofilms that coat systemic epithelial surfaces in urinary tract, bladder, ear, and the respiratory tract.  See reboot the gut.

21.  Xylitol nasal spray (XNS), when used repeatedly, is effective for quickly clearing sinus infections and makes microbiome less plaque forming. Xylitol induces bacteria gene expression changes that may last for weeks to months.  Plaque molecules are also called endotoxins, which play a role in causing inflammation and predisposing to ear infections. Xylitol reprograms bacteria to stop making plaques and endotoxins. See Amazon Reviews for Case Histories: XNS Amazon Reviews  See for how it works. How to make nasal spray:  Recipe. More facts see  our Xylitol summary.


This website contains the following table of Antibiotics Vs. Pulmonary Microbes:
“Table 2: Oral Antibiotics Used in the Treatment of Acute Exacerbations of Chronic Bronchitis


Spectrum of Activity and Resistance Pattern






No activity against atypical and beta-lactamase-producing bacteria
Penicillin resistance concerning with Streptococcus pneumoniae
Limited activity against Enterobacteriaceae

Resistance limits use


Activity against major pathogens
No activity against atypical bacteria: Mycoplasma
Penicillin resistance concerning with S. pneumoniae
Moderate activity against Enterobacteriaceae

More costly
Gastrointestinal side effects





Activity against major pathogens
No activity against atypical bacteria: Mycoplasma
Resistance concerning with Strep. pneumoniae
Moderate activity against Enterobacteriaceae

Alternative to beta-lactam agents and generally as effective

Second Generation




Can be destroyed by Haemophilus influenzae and Moraxella catarrhalis enzymes

Associated with failure in patients with severe disease


Moderate H. influenzae activity






Moderate H. influenzae activity


Third Generation







No activity against Staphylococcus aureus
Marginal activity against Strep. pneumoniae

Poor gram-positive activity limits use


Poor activity against S. aureus







Active against Mycobacterium avium. M. kansaii


Macrolide resistance concerning with S.pneumoniae
Active against atypical organisms: Mycoplasma
Not active against Enterobacteriaceae



Greatest activity against H. influenzae

Short course of 3-5 days may be used.  Long term may cause hearing loss.


Greatest activity against S. pneumoniae

Alteration of taste may be an issue with bid dosing


Poor activity against H. influenzae

Limited spectrum of activity





Covers major pathogens and atypical organisms: Mycoplasma; S. pneumoniae resistance is common

Maybe an alternative to quinolones and macrolides when atypical coverage is needed. See PMID: 21977068


Similar to doxycycline



Limited activity against major pathogens
Active against atypical bacteria: Mycoplasma

Limited spectrum of activity





Active against all major pathogens, atypical pathogens, Enterobacteriaceae, and Pseudomonas aeruginosa



Least active against Strep. pneumoniae
Greatest activity against P. aeruginosa

Use if P. aeruginosa coverage is required


Enhanced gram-positive activity






Greatest activity against Streptococcus pneumoniae






Covers major pathogens
No atypical coverage: Mycoplasma
Streptococcus pneumoniae resistance is common

Resistance limits use


Dr Frederick Klenner: (1953) Early Clinical Usage of Vitamin C.  Quote:

“Our interest with vitamin C against the virus organism began ten years ago in a modest rural home. Here a patient who was receiving symptomatic treatment for virus pneumonia had suddenly developed cyanosis. He refused hospitalization for supportive oxygen therapy. X-Ray had been considered because of its dubious value and because the nearest department equipped to give such treatment was 69 miles distant. Two grams of vitamin C was given intramuscularly with the hope that the anaerobic condition existing in the tissues would be relieved by the catalytic action of vitamin C acting as a gas transport aid in cellular respiration.

“This was an old idea; the important factor being that it worked. Within 30 minutes after giving the drug (which was carried in my medical bag for the treatment of diarrhea in children) the characteristic breathing and slate-like color had cleared.

“Returning six hours later, at eight in the evening, the patient was found sitting over the edge of his bed enjoying a late dinner. Strangely enough his fever was three degrees less than it was at 2 P.M. that same afternoon. This sudden change in the condition of the patient led us to suspect that vitamin C was playing a role of far greater significance than that of a simple respiratory catalyst.

“A second injection of one gram of vitamin C was administered, by the same route, on this visit and then subsequently at six hour intervals for the next three days. This patient was clinically well after 36 hours of chemotherapy. From this casual observation we have been able to assemble sufficient clinical evidence that prove unequivocally that vitamin C is the antibiotic of choice in the handling of all types of virus diseases. Furthermore it is a major adjuvant in the treatment of at other infectious diseases.

“This experimental “strike” on vitamin C as an antibiotic opened a new avenue of approach to the problem of dealing with the virus bodies. With a great deal of enthusiasm we decided to try its effectiveness with all of the childhood diseases.

“Measles was singled out more so than the others because of the knowledge that it was a small virus like the one causing poliomyelitis. It was reasonable to assume that if measles could be controlled then Poliomyelitis, too, would have a drug that could prevent as well as cure the disease.

“The use of vitamin C in measles proved to be medical curiosity. For the first time a virus infection could be handled as if it were a dog on a leash. In the Spring of 1948 measles was running in epidemic proportions in this section of the country. Our first act, then, was to have our own little daughters play with children known to be in the “contagious phase.” When the syndrome of fever redness of the eyes and throat, catarrh, spasmodic bronchial cough and Koplik spots had developed and the children were obviously sick, vitamin C was started.

“In this experiment it was found that 1000mg every four hours, by mouth, would modify the attack. Smaller doses allowed the disease to progress. When 1000mg was given every two hours all evidence of the infection cleared in 48 hours. If the drug was then discontinued for a similar period (48 hours) the above syndrome returned.

“We observed this of and on picture for thirty days at which time the drug (vitamin C) was given 1000 mg every 2 hours around the clock for four days. This time the picture cleared and did not return.

“These little girls did not develop the measles rash during the above experiment and although exposed many times since still maintain this “immunity.” Late cases were given the vitamin by needle. The results proved to be even more dramatic. Given by injection the same complete control of the measles syndrome was in evidence a 24 and 36 hour periods, depending entirely on the amount employed and the frequency of the administration.

“Aborting of these cases before the development of the rash apparently gives no interference to the development of immunity. Recent progress on the rapidity of growth (a development) of the virus bodies by means of the electronic microscope makes intelligent the failure experienced by earlier workers when employing vitamin C on the virus organism (or bodies). Unless the virus is completely destroyed, as demonstrated in the experiments with the virus using measles, the infection will again manifest itself after a short incubation period. Small, single daily doses do not even modify the course of the infection.” 


Note Recent PubMed article states:  “The blood half life of vitamin C is 30 minutes” with no intake.


See Vitamin C Foundation:  It’s the Dosage Stupid. 

If the AA dosage is low or infrequent, AA does not work effectively as an antibiotic and an antiviral.  AA at nutritional levels is never enough AA blood concentration to work as an antibiotic/antiviral. Thus the poor results in study after study. Once the proper AA blood concentrations are maintained by frequent AA intake, then the remarkable healing actions of AA become evident.  See:  How much vitamin C.

We have observed a COPD exacerbation due to AA depletion accompanied by systemic (Cypro-induced endotoxin) toxemia and with serious congestive heart/lung dysfunctions.  Once enough AA was administered every 2 hours, with CoQ10 supplementation, and Angiotensin Release Blockers (ARBs) blocked the cytokine inflammation cascade, continued IV antibiotics for several days, oxygen therapy, recovery of heart and lung function was remarkably swift, and to a improved level of respiratory functioning. The needed AA level to sustain the recovery was greater than 12 grams per day for 135-pound patient.  Dosage: 1-3 grams of AA every 1-3 waking hour and AA during the night if awakened to relieve bladder. Liposomal AA would provide better pharmacokinetics at a lower AA dosage.



  1. National Accademy of Sciences: Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virusinduced inflammation and infection
  2. Journal of Biological Chemistry: Pulmonary Surfactant Phosphatidylglycerol Inhibits Mycoplasma pneumoniae-stimulated Eicosanoid Production from Human and Mouse Macrophages  
  3.  Quote:

“The properties that determine the anti-infective action of lipids are related to their structure, e.g., monoglycerides, free fatty acids. The monoglycerides are active; diglycerides and triglycerides are inactive. Of the saturated fatty acids, lauric acid(C-12) has greater antiviral activity than caprylic acid (C-8), capric acid (C-10) or myristic acid (C-14).  In general, it is reported that the fatty acids and monoglycerides produce their killing/inactivating effect by lysing the plasma membrane lipid bilayer. The antiviral action attributed to monolaurin is that of solubilising the lipids and phospholipids in the envelope of the virus, causing the disintegration of the virus envelope. However, there is evidence from recent studies that one antimicrobial effect in bacteria is related to monolaurin's interference with signal transduction (Projan et al., 1994), and another antimicrobial effect in viruses is due to lauric acid's interference with virus assembly and viral maturation (Hornung et al., 1994).”

  1. Pharmacologial and Dietary Antioxidant Therapies for Chronic Obstructive Pulmonary Disease. PubMed

Abstract  The progression and exacerbations of chronic obstructive pulmonary disease (COPD) are intimately associated with tobacco smoke/biomass fuel-induced oxidative and aldehyde/carbonyl stress. Alterations in redox signaling pro-inflammatory kinases and transcription factors, steroid resistance, unfolded protein response, mucus hypersecretion, extracellular matrix remodeling, autophagy/ apoptosis, epigenetic changes, cellular senescence/aging, endothelial dysfunction, autoimmunity, and skeletal muscle dysfunction are some of the pathological hallmarks of COPD. In light of the above it would be prudent to target systemic and local oxidative stress with agents that can modulate the antioxidants/redox system or by boosting the endogenous levels of antioxidants for the treatment and management of COPD. Identification of various antioxidant agents, such as thiol molecules (glutathione and mucolytic drugs, such as Nacetyl-L-cysteine and N-acystelyn, erdosteine, fudosteine, ergothioneine, and carbocysteine lysine salt), dietary natural product-derived polyphenols and other compounds (curcumin, resveratrol, green tea catechins, quercetin sulforaphane, lycopene, acai, alpha-lipoic acid, tocotrienols, and apocynin) have made it possible to modulate various biochemical aspects of COPD. Various researches and clinical trials have revealed that these antioxidants can detoxify free radicals and oxidants, control expression of redox and glutathione biosynthesis genes, chromatin remodeling, and ultimately inflammatory gene expression. In addition, modulation of cigarette smoke induced oxidative stress and related cellular changes have also been reported to be effected by synthetic molecules. This includes specific spin traps like α- phenyl-N-tert-butyl nitrone, a catalytic antioxidant (ECSOD mimetic), porphyrins (AEOL 10150 and AEOL 10113), and a superoxide dismutase mimetic M40419, lipid peroxidation and protein carbonylation blockers/inhibitors, such as edaravone and lazaroids/tirilazad, myeloperoxidase inhibitors, as well as specialized pro-resolving mediators/inflammatory resolving lipid mediators, omega-3 fatty acids, vitamin D, and hydrogen sulfide. According to various studies it appears that the administration of multiple antioxidants could be a more effective mode used in the treatment of COPD. In this review, various pharmacological and dietary approaches to enhance lung antioxidant levels and beneficial effects of antioxidant therapeutics in treatment or intervening the progression of COPD have been discussed.


  1. Future therapeutic treatment of COPD: Struggle between oxidants and cytokines
  2. Weston A Links to ABCs-of-Nutrition via WaybackMachine Web Archive.
  4. Mary Enig’s Papers: Google[enig coconut antiviral]


References to our website content:

  1. AA Ketosis and Multi-factored protocol Theory and practical considerations.
  2. Nutritional, Orthomolecular and Complementary Medicine Reference web links.
  3. AA Pharmacokintetics and Pharmacodynamics
  4. Oils Nutrition Update Surprise!  Saturated fats are antimicrobial foods, good for you.
  5. Plaque and Biofilm antibiotic resistance: Serrapeptase description and Case Histories Links
  6. Gut Health Case Histories Reboot the gut for better lower spine health.
  7. Heart Disease Case History Linus Pauling’s analysis, functional chemistry.
  8. Dr Klenner’s Ascorbic Acid (AA) Case Histories Links: Anti-biotic, -toxin, -viral.


More Klenner on Nutrition:

Also see:  Multiple sclerosis and myasthenia gravis recovery nutritional guidelines for vitamin dependencies where a much higher than normal dosage is therapeutic if given over a long enough time of several years.



Other References:

  2.  POPG chemistry.
  3.  Chlamydia pneumonia chronic infection support group.
  4. Fermented Cabbage Discussion Forum.





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